<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Ebel S</dc:creator>
  <dc:creator>Dufke J</dc:creator>
  <dc:creator>Köhler B</dc:creator>
  <dc:creator>Preim B</dc:creator>
  <dc:creator>Rosemeier S</dc:creator>
  <dc:creator>Jung B</dc:creator>
  <dc:creator>Dähnert I</dc:creator>
  <dc:creator>Lurz P</dc:creator>
  <dc:creator>Borger M</dc:creator>
  <dc:creator>Grothoff M</dc:creator>
  <dc:creator>Gutberlet M</dc:creator>
  <dc:date>2019</dc:date>
  <dc:description xmlns:ns0="xml" ns0:lang="en">To compare two broadly used 4D-flow- with a 2D-flow-sequence in healthy volunteers, regarding absolute flow parameters, image quality (IQ), and eddy current correction (ECC). Forty volunteers (42 ± 11.8 years, 22 females) were examined with a 3T scanner. Thoracic aortic flow was assessed using a 3D-T2w-SPACE-STIR-sequence for morphology and two accelerated 4D-flow sequences for comparison, one with k-t undersampling and one with standard GRAPPA parallel-imaging. 2D-flow was used as reference standard. The custom-made software tool Bloodline enabled flow measurements for all analyses at the same location. Quantitative flow analyses were performed with and without ECC. One reader assessed pathline IQ (IQ-PATH) and occurrence of motion artefacts (IQ-ART) on a 3-point grading scale, the higher the better. k-t GRAPPA allowed a significant mean scan time reduction of 46% (17:56 ± 5:26 min vs. 10:40 ± 3:15 min) and provided significantly fewer motion artefacts than standard GRAPPA (IQ-ART 1.57 ± 0.55 vs. 0.84 ± 0.48; p &lt; 0.001). Neither 4D-flow sequence significantly differed in flow volume nor peak velocity results with or without ECC. Nevertheless, the correlation between both 4D-flow sequences and 2D-flow was better with ECC; the k-t GRAPPA sequence performed best (R = 0.96 vs. 0.90). k-t GRAPPA 4D-flow was not inferior to a standard GRAPPA-sequence, showed fewer artefacts, comparable IQ and was almost two-fold faster.</dc:description>
  <dc:format>application/pdf</dc:format>
  <dc:identifier>https://sonar.ch/global/documents/46895</dc:identifier>
  <dc:language>eng</dc:language>
  <dc:relation>info:eu-repo/semantics/altIdentifier/doi/10.1038/s41598-019-45196-x</dc:relation>
  <dc:relation>info:eu-repo/semantics/altIdentifier/pmid/31201339</dc:relation>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:source>Scientific reports. - 2019</dc:source>
  <dc:subject xmlns:ns1="xml" ns1:lang="en">Adult</dc:subject>
  <dc:subject xmlns:ns2="xml" ns2:lang="en">Aorta</dc:subject>
  <dc:subject xmlns:ns3="xml" ns3:lang="en">Artifacts</dc:subject>
  <dc:subject xmlns:ns4="xml" ns4:lang="en">Coronary Circulation</dc:subject>
  <dc:subject xmlns:ns5="xml" ns5:lang="en">Female</dc:subject>
  <dc:subject xmlns:ns6="xml" ns6:lang="en">Humans</dc:subject>
  <dc:subject xmlns:ns7="xml" ns7:lang="en">Image Interpretation, Computer-Assisted</dc:subject>
  <dc:subject xmlns:ns8="xml" ns8:lang="en">Linear Models</dc:subject>
  <dc:subject xmlns:ns9="xml" ns9:lang="en">Male</dc:subject>
  <dc:subject xmlns:ns10="xml" ns10:lang="en">Reproducibility of Results</dc:subject>
  <dc:subject xmlns:ns11="xml" ns11:lang="en">Systole</dc:subject>
  <dc:subject xmlns:ns12="xml" ns12:lang="en">Time Factors</dc:subject>
  <dc:title xmlns:ns13="xml" ns13:lang="en">Comparison of two accelerated 4D-flow sequences for aortic flow quantification.</dc:title>
  <dc:type>http://purl.org/coar/resource_type/c_6501</dc:type>
</oai_dc:dc>