<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Goetti R</dc:creator>
  <dc:creator>Feuchtner G</dc:creator>
  <dc:creator>Stolzmann P</dc:creator>
  <dc:creator>Donati OF</dc:creator>
  <dc:creator>Wieser M</dc:creator>
  <dc:creator>Plass A</dc:creator>
  <dc:creator>Frauenfelder T</dc:creator>
  <dc:creator>Leschka S</dc:creator>
  <dc:creator>Alkadhi H</dc:creator>
  <dc:date>2011</dc:date>
  <dc:description xmlns:ns0="xml" ns0:lang="en">OBJECTIVES
To evaluate the accuracy of high-pitch delayed enhancement (DE) CT for the assessment of myocardial viability with MRI as the reference standard.


METHODS
Twenty-four patients (mean age 66.9 ± 9.2 years) with coronary artery disease underwent DE imaging with 128-slice dual-source CT (prospective electrocardiography (ECG)-triggering) and MRI at 1.5 T. Two observers assessed DE transmurality per segment, and measured signal intensity (MRI) or attenuation (CT) in infarcted and healthy myocardium and noise in the left ventricular blood pool for calculating contrast-to-noise ratios (CNR).


RESULTS
75/408 (18.4%) segments in 18/24 patients (75.0%) showed DE in MRI, of which 28 segments in 10/24 (41.7%) patients were non-viable (scar tissue transmurality &gt;50%). Sensitivity, specificity and accuracy of CT for diagnosis of non-viability were 60.7%, 96.8% and 94.4% per segment, and 90.0%, 92.9% and 91.7% per patient. CNR was significantly higher in MR (7.4 ± 3.0 vs. 4.6 ± 1.5; p = 0.018), and image noise significantly lower (11.6 ± 5.7 vs.15.0 ± 4.5; p = 0.019). Radiation dose of DECT was 0.89 ± 0.07 mSv.


CONCLUSIONS
CTDE imaging in the high-pitch mode enables myocardial viability assessment at a low radiation dose and good accuracy compared with MR, although associated with a lower CNR and higher noise.</dc:description>
  <dc:format>application/pdf</dc:format>
  <dc:identifier>https://sonar.ch/global/documents/47658</dc:identifier>
  <dc:language>eng</dc:language>
  <dc:relation>info:eu-repo/semantics/altIdentifier/doi/10.1007/s00330-011-2149-8</dc:relation>
  <dc:relation>info:eu-repo/semantics/altIdentifier/pmid/21573970</dc:relation>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:source>European radiology. - 2011</dc:source>
  <dc:subject xmlns:ns1="xml" ns1:lang="en">Aged</dc:subject>
  <dc:subject xmlns:ns2="xml" ns2:lang="en">Aged, 80 and over</dc:subject>
  <dc:subject xmlns:ns3="xml" ns3:lang="en">Algorithms</dc:subject>
  <dc:subject xmlns:ns4="xml" ns4:lang="en">Coronary Artery Bypass</dc:subject>
  <dc:subject xmlns:ns5="xml" ns5:lang="en">Coronary Artery Disease</dc:subject>
  <dc:subject xmlns:ns6="xml" ns6:lang="en">Electrocardiography</dc:subject>
  <dc:subject xmlns:ns7="xml" ns7:lang="en">Female</dc:subject>
  <dc:subject xmlns:ns8="xml" ns8:lang="en">Humans</dc:subject>
  <dc:subject xmlns:ns9="xml" ns9:lang="en">Magnetic Resonance Imaging</dc:subject>
  <dc:subject xmlns:ns10="xml" ns10:lang="en">Male</dc:subject>
  <dc:subject xmlns:ns11="xml" ns11:lang="en">Middle Aged</dc:subject>
  <dc:subject xmlns:ns12="xml" ns12:lang="en">Myocardium</dc:subject>
  <dc:subject xmlns:ns13="xml" ns13:lang="en">Preoperative Period</dc:subject>
  <dc:subject xmlns:ns14="xml" ns14:lang="en">Reference Standards</dc:subject>
  <dc:subject xmlns:ns15="xml" ns15:lang="en">Reproducibility of Results</dc:subject>
  <dc:subject xmlns:ns16="xml" ns16:lang="en">Tomography, X-Ray Computed</dc:subject>
  <dc:title xmlns:ns17="xml" ns17:lang="en">Delayed enhancement imaging of myocardial viability: low-dose high-pitch CT versus MRI.</dc:title>
  <dc:type>http://purl.org/coar/resource_type/c_6501</dc:type>
</oai_dc:dc>