<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Canal CW</dc:creator>
  <dc:creator>Weber MN</dc:creator>
  <dc:creator>Cibulski SP</dc:creator>
  <dc:creator>Silva MS</dc:creator>
  <dc:creator>Puhl DE</dc:creator>
  <dc:creator>Stalder H</dc:creator>
  <dc:creator>Peterhans E</dc:creator>
  <dc:date>2017</dc:date>
  <dc:description xmlns:ns0="xml" ns0:lang="en">Hepatitis C virus (HCV) (genus Hepacivirus; family Flaviviridae) is a major human pathogen causing persistent infection and hepatic injury. Recently, emerging HCV-like viruses were described infecting wild animals, such as bats and rodents, and domestic animals, including dogs, horses, and cattle. Using degenerate primers for detecting bovine pestiviruses in a 1996 survey three bovine serum samples showed a low identity with the genus Pestivirus of the Flaviviridae family. A virus could not be isolated in cell culture. The description of bovine hepaciviruses (BovHepV) in 2015 allowed us to retrospectively identify the sequences as BovHepV, with a 88.9% nucleotide identity. In a reconstructed phylogenetic tree, the Brazilian BovHepV samples grouped within the bovine HCV-like cluster in a separated terminal node that was more closely related to the putative bovine Hepacivirus common ancestor than to bovine hepaciviruses detected in Europe and Africa.</dc:description>
  <dc:format>application/pdf</dc:format>
  <dc:identifier>https://sonar.ch/global/documents/60375</dc:identifier>
  <dc:language>eng</dc:language>
  <dc:relation>info:eu-repo/semantics/altIdentifier/doi/10.1155/2017/4732520</dc:relation>
  <dc:relation>info:eu-repo/semantics/altIdentifier/pmid/28904959</dc:relation>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:source>BioMed research international. - 2017</dc:source>
  <dc:subject xmlns:ns1="xml" ns1:lang="en">Animals</dc:subject>
  <dc:subject xmlns:ns2="xml" ns2:lang="en">Brazil</dc:subject>
  <dc:subject xmlns:ns3="xml" ns3:lang="en">Cattle</dc:subject>
  <dc:subject xmlns:ns4="xml" ns4:lang="en">Dogs</dc:subject>
  <dc:subject xmlns:ns5="xml" ns5:lang="en">Genetic Variation</dc:subject>
  <dc:subject xmlns:ns6="xml" ns6:lang="en">Genome, Viral</dc:subject>
  <dc:subject xmlns:ns7="xml" ns7:lang="en">Hepacivirus</dc:subject>
  <dc:subject xmlns:ns8="xml" ns8:lang="en">Hepatitis C</dc:subject>
  <dc:subject xmlns:ns9="xml" ns9:lang="en">Horses</dc:subject>
  <dc:subject xmlns:ns10="xml" ns10:lang="en">Humans</dc:subject>
  <dc:subject xmlns:ns11="xml" ns11:lang="en">Phylogeny</dc:subject>
  <dc:title xmlns:ns12="xml" ns12:lang="en">A Novel Genetic Group of Bovine Hepacivirus in Archival Serum Samples from Brazilian Cattle.</dc:title>
  <dc:type>http://purl.org/coar/resource_type/c_6501</dc:type>
</oai_dc:dc>
