<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Debray TP</dc:creator>
  <dc:creator>Moons KG</dc:creator>
  <dc:creator>van Valkenhoef G</dc:creator>
  <dc:creator>Efthimiou O</dc:creator>
  <dc:creator>Hummel N</dc:creator>
  <dc:creator>Groenwold RH</dc:creator>
  <dc:creator>Reitsma JB</dc:creator>
  <dc:date>2015</dc:date>
  <dc:description xmlns:ns0="xml" ns0:lang="en">Individual participant data (IPD) meta-analysis is an increasingly used approach for synthesizing and investigating treatment effect estimates. Over the past few years, numerous methods for conducting an IPD meta-analysis (IPD-MA) have been proposed, often making different assumptions and modeling choices while addressing a similar research question. We conducted a literature review to provide an overview of methods for performing an IPD-MA using evidence from clinical trials or non-randomized studies when investigating treatment efficacy. With this review, we aim to assist researchers in choosing the appropriate methods and provide recommendations on their implementation when planning and conducting an IPD-MA.</dc:description>
  <dc:identifier>https://sonar.ch/global/documents/60864</dc:identifier>
  <dc:language>eng</dc:language>
  <dc:relation>info:eu-repo/semantics/altIdentifier/doi/10.1002/jrsm.1160</dc:relation>
  <dc:relation>info:eu-repo/semantics/altIdentifier/pmid/26287812</dc:relation>
  <dc:source>Research synthesis methods. - 2015</dc:source>
  <dc:subject xmlns:ns1="xml" ns1:lang="en">IPD</dc:subject>
  <dc:subject xmlns:ns2="xml" ns2:lang="en">NRSI</dc:subject>
  <dc:subject xmlns:ns3="xml" ns3:lang="en">RCT</dc:subject>
  <dc:subject xmlns:ns4="xml" ns4:lang="en">cross-design</dc:subject>
  <dc:subject xmlns:ns5="xml" ns5:lang="en">evidence synthesis</dc:subject>
  <dc:subject xmlns:ns6="xml" ns6:lang="en">meta-analysis</dc:subject>
  <dc:subject xmlns:ns7="xml" ns7:lang="en">non-randomized intervention studies</dc:subject>
  <dc:subject xmlns:ns8="xml" ns8:lang="en">review</dc:subject>
  <dc:subject xmlns:ns9="xml" ns9:lang="en">Data Interpretation, Statistical</dc:subject>
  <dc:subject xmlns:ns10="xml" ns10:lang="en">Humans</dc:subject>
  <dc:subject xmlns:ns11="xml" ns11:lang="en">Linear Models</dc:subject>
  <dc:subject xmlns:ns12="xml" ns12:lang="en">Meta-Analysis as Topic</dc:subject>
  <dc:subject xmlns:ns13="xml" ns13:lang="en">Models, Statistical</dc:subject>
  <dc:subject xmlns:ns14="xml" ns14:lang="en">Proportional Hazards Models</dc:subject>
  <dc:subject xmlns:ns15="xml" ns15:lang="en">Randomized Controlled Trials as Topic</dc:subject>
  <dc:subject xmlns:ns16="xml" ns16:lang="en">Software</dc:subject>
  <dc:subject xmlns:ns17="xml" ns17:lang="en">Treatment Outcome</dc:subject>
  <dc:title xmlns:ns18="xml" ns18:lang="en">Get real in individual participant data (IPD) meta-analysis: a review of the methodology.</dc:title>
  <dc:type>http://purl.org/coar/resource_type/c_6501</dc:type>
</oai_dc:dc>
