<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Wiegand A</dc:creator>
  <dc:creator>Attin T</dc:creator>
  <dc:date>2014</dc:date>
  <dc:description xmlns:ns0="xml" ns0:lang="en">OBJECTIVES
This randomised in situ study aimed to analyse the effect of milk (with or without 5ppm F) and CPP-ACP pastes (with or without 900ppm F) on dental erosion.


METHODS
The study was a seven phase (5 days each) crossover design involving 15 participants wearing intraoral appliances with enamel and dentine specimens. Specimens were extraorally eroded (erosive soft drink, 6×90s/day) and brushed (2×30s/day, 2N) using a non-fluoridated toothpaste (negative control). The test products were milk, milk+5ppm F (twice daily, each 100ml/2min), CPP-ACP paste, CPP-ACP paste+900ppm F (3min/day) or a SnCl2/AmF/NaF mouthrinse (positive control, 30s/day), which were applied immediately after erosion with the appliances in the oral cavity. In an additional group, a fluoridated toothpaste was used without any additional test product. Tissue loss was determined profilometrically after 5 days and statistically analysed by linear mixed models methodologies (p&lt;0.05).


RESULTS
Compared with the negative control (non-fluoridated toothpaste only, enamel: 2.2±1.3μm; dentine: 3.8±2.2μm), enamel and dentine loss was significantly reduced by the use of fluoridated toothpaste (enamel: 1.1±1.0μm; dentine: 2.4±1.7μm) and the SnCl2/AmF/NaF mouthrinse (1.5±1.5μm; dentine: 1.8±1.9μm).


CONCLUSIONS
Milk and CPP-ACP were not effective in reducing enamel and dentine loss significantly, independently of the presence of fluoride.


CLINICAL SIGNIFICANCE
Enamel and dentine erosion were significantly reduced by the use of a fluoridated toothpaste or a SnCl2/AmF/NaF mouthrinse, but not by milk or CPP-ACP under the conditions of the present study.


CLINICAL TRIALS REGISTRATION
NCT01566357.</dc:description>
  <dc:format>application/pdf</dc:format>
  <dc:identifier>https://sonar.ch/global/documents/66251</dc:identifier>
  <dc:language>eng</dc:language>
  <dc:relation>info:eu-repo/semantics/altIdentifier/doi/10.1016/j.jdent.2014.07.009</dc:relation>
  <dc:relation>info:eu-repo/semantics/altIdentifier/pmid/25038509</dc:relation>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:source>Journal of dentistry. - 2014</dc:source>
  <dc:subject xmlns:ns1="xml" ns1:lang="en">Calcium</dc:subject>
  <dc:subject xmlns:ns2="xml" ns2:lang="en">Demineralization</dc:subject>
  <dc:subject xmlns:ns3="xml" ns3:lang="en">Dentine</dc:subject>
  <dc:subject xmlns:ns4="xml" ns4:lang="en">Enamel</dc:subject>
  <dc:subject xmlns:ns5="xml" ns5:lang="en">Fluoride</dc:subject>
  <dc:subject xmlns:ns6="xml" ns6:lang="en">Phosphate</dc:subject>
  <dc:subject xmlns:ns7="xml" ns7:lang="en">Adult</dc:subject>
  <dc:subject xmlns:ns8="xml" ns8:lang="en">Amines</dc:subject>
  <dc:subject xmlns:ns9="xml" ns9:lang="en">Animals</dc:subject>
  <dc:subject xmlns:ns10="xml" ns10:lang="en">Cariostatic Agents</dc:subject>
  <dc:subject xmlns:ns11="xml" ns11:lang="en">Caseins</dc:subject>
  <dc:subject xmlns:ns12="xml" ns12:lang="en">Cattle</dc:subject>
  <dc:subject xmlns:ns13="xml" ns13:lang="en">Cross-Over Studies</dc:subject>
  <dc:subject xmlns:ns14="xml" ns14:lang="en">Dental Enamel</dc:subject>
  <dc:subject xmlns:ns15="xml" ns15:lang="en">Dentin</dc:subject>
  <dc:subject xmlns:ns16="xml" ns16:lang="en">Female</dc:subject>
  <dc:subject xmlns:ns17="xml" ns17:lang="en">Fluorides</dc:subject>
  <dc:subject xmlns:ns18="xml" ns18:lang="en">Humans</dc:subject>
  <dc:subject xmlns:ns19="xml" ns19:lang="en">Male</dc:subject>
  <dc:subject xmlns:ns20="xml" ns20:lang="en">Milk</dc:subject>
  <dc:subject xmlns:ns21="xml" ns21:lang="en">Mouthwashes</dc:subject>
  <dc:subject xmlns:ns22="xml" ns22:lang="en">Prospective Studies</dc:subject>
  <dc:subject xmlns:ns23="xml" ns23:lang="en">Single-Blind Method</dc:subject>
  <dc:subject xmlns:ns24="xml" ns24:lang="en">Sodium Fluoride</dc:subject>
  <dc:subject xmlns:ns25="xml" ns25:lang="en">Tin Compounds</dc:subject>
  <dc:subject xmlns:ns26="xml" ns26:lang="en">Tooth Abrasion</dc:subject>
  <dc:subject xmlns:ns27="xml" ns27:lang="en">Tooth Erosion</dc:subject>
  <dc:subject xmlns:ns28="xml" ns28:lang="en">Toothpastes</dc:subject>
  <dc:title xmlns:ns29="xml" ns29:lang="en">Randomised in situ trial on the effect of milk and CPP-ACP on dental erosion.</dc:title>
  <dc:type>http://purl.org/coar/resource_type/c_6501</dc:type>
</oai_dc:dc>