<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Özbay PS</dc:creator>
  <dc:creator>Duerst Y</dc:creator>
  <dc:creator>Wilm BJ</dc:creator>
  <dc:creator>Pruessmann KP</dc:creator>
  <dc:creator>Nanz D</dc:creator>
  <dc:date>2018</dc:date>
  <dc:description xmlns:ns0="xml" ns0:lang="en">PURPOSE
To assess the potential of a real-time field-control (FC) system for mitigating effects of spatiotemporal field fluctuations in quantitative susceptibility mapping (QSM) at 7 T.


METHODS
Magnitude, phase, and QSM images of phantoms and healthy volunteers were acquired under standard conditions and under induced field perturbation (FP) (phantoms: periodic water-bottle displacement; volunteers: deep breathing and forearm movement) with and without FC, which continuously detects and minimizes magnetic-field variations.


RESULTS
Field control successfully eliminated FP-induced impairment of phantom image quality and deviations from a linear susceptibility increase for increasing gadolinium concentration in a Gd dilution series (y = 320x - 0.60, R2  = 0.93 for the scan with FP and FC versus y = 259x - 0.54, R2  = 0.78 for the scan with FP and no FC (slope literature value: 326 ppm L/mol)). Similarly, in volunteers, FC allowed a recovery of a FP-induced loss of identifiable brain structures and reduced the relative change of mean susceptibilities and standard deviations (93 ± 53% to 34 ± 46%) in all regions of interests with respect to the reference scan.


CONCLUSIONS
Real-time FC improved the delineation of brain structures and the match of susceptibility values with reference values obtained without FP. Magn Reson Med 79:770-778, 2018. © 2017 International Society for Magnetic Resonance in Medicine.</dc:description>
  <dc:identifier>https://sonar.ch/global/documents/71860</dc:identifier>
  <dc:language>eng</dc:language>
  <dc:relation>info:eu-repo/semantics/altIdentifier/doi/10.1002/mrm.26735</dc:relation>
  <dc:relation>info:eu-repo/semantics/altIdentifier/pmid/28556247</dc:relation>
  <dc:source>Magnetic resonance in medicine. - 2018</dc:source>
  <dc:subject xmlns:ns1="xml" ns1:lang="en">7 T</dc:subject>
  <dc:subject xmlns:ns2="xml" ns2:lang="en">NMR field probes</dc:subject>
  <dc:subject xmlns:ns3="xml" ns3:lang="en">field control</dc:subject>
  <dc:subject xmlns:ns4="xml" ns4:lang="en">gradient echo</dc:subject>
  <dc:subject xmlns:ns5="xml" ns5:lang="en">phase</dc:subject>
  <dc:subject xmlns:ns6="xml" ns6:lang="en">quantitative susceptibility mapping (QSM)</dc:subject>
  <dc:subject xmlns:ns7="xml" ns7:lang="en">Algorithms</dc:subject>
  <dc:subject xmlns:ns8="xml" ns8:lang="en">Brain</dc:subject>
  <dc:subject xmlns:ns9="xml" ns9:lang="en">Humans</dc:subject>
  <dc:subject xmlns:ns10="xml" ns10:lang="en">Image Processing, Computer-Assisted</dc:subject>
  <dc:subject xmlns:ns11="xml" ns11:lang="en">Magnetic Resonance Imaging</dc:subject>
  <dc:subject xmlns:ns12="xml" ns12:lang="en">Phantoms, Imaging</dc:subject>
  <dc:title xmlns:ns13="xml" ns13:lang="en">Enhanced quantitative susceptibility mapping (QSM) using real-time field control.</dc:title>
  <dc:type>http://purl.org/coar/resource_type/c_6501</dc:type>
</oai_dc:dc>
