Moser B Brandes M 2006 A subtype of activated human gammadelta T cells, termed Vdelta2+ T cells, has antigen-presentation features similar in potency and efficacy to those seen in dendritic cells. Comparable treatment of alphabeta T cells does not result in 'professional' antigen presenting cells (APCs). What is so special about Vdelta2+ T cells? How do they acquire these unexpected properties? Under what physiological conditions would such a bridge between innate and adaptive immunity come into play? In addition to discussing these questions, we introduce a model that correlates the expression of lymph node homing receptors in Vdelta2+ T cells with the involvement of this alternative type of APC in anti-microbial alphabeta T cell responses. https://sonar.ch/global/documents/79504 eng info:eu-repo/semantics/altIdentifier/doi/10.1016/j.it.2006.01.002 info:eu-repo/semantics/altIdentifier/pmid/16442347 Trends in immunology. - 2006 Antigen Presentation Antigen-Presenting Cells Chemokines Humans Lymphocyte Activation Models, Immunological Receptors, Antigen, T-Cell, gamma-delta T-Lymphocytes Gammadelta T cells: an alternative type of professional APC. http://purl.org/coar/resource_type/c_6501