Padeste C Steiger B Grubelnik A Tiefenauer L 2003 Conjugates of avidin with ferrocene and with microperoxidase 8 have been used as electrochemically active molecular building blocks. Assemblies of the conjugates with biotinylated glucose oxidase or lactate oxidase on gold electrodes were tested as enzyme sensors for glucose and lactate. The electrochemical detection is based either on ferrocene-mediated oxidation of the substrate in oxygen-free solution, or on microperoxidase-catalysed reduction of H2O2 which is enzymatically produced from the substrate and molecular oxygen. Glucose and lactate were detectable with both detection principles in concentrations down to 1 or 0.1 mM, respectively. The molecular architecture concept allows quick adaptation of the sensors to other analytes, and it provides a platform for arrays of sensors with different selectivity. https://sonar.ch/global/documents/83201 eng info:eu-repo/semantics/altIdentifier/doi/10.1016/s0956-5663(03)00214-8 info:eu-repo/semantics/altIdentifier/pmid/14611760 Biosensors & bioelectronics. - 2003 Avidin Biosensing Techniques Coated Materials, Biocompatible Enzymes, Immobilized Equipment Design Equipment Failure Analysis Feasibility Studies Ferrous Compounds Glucose Glucose Oxidase Lactic Acid Metallocenes Microchemistry Mixed Function Oxygenases Oxidation-Reduction Peroxidases Reproducibility of Results Sensitivity and Specificity Staining and Labeling Redox labelled avidin for enzyme sensor architectures. http://purl.org/coar/resource_type/c_6501