<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Benjamin D</dc:creator>
  <dc:creator>Hall MN</dc:creator>
  <dc:date>2013</dc:date>
  <dc:description xmlns:ns0="xml" ns0:lang="en">mTOR is a central controller that integrates many inputs to regulate cell growth and ensure cellular homeostasis. The mTORC1 inhibitor TSC (tuberous sclerosis complex) on the peroxisome is found to inhibit mTORC1 in response to endogenous reactive oxygen species. Thus, mTOR may avoid confounding different inputs by sensing them at different cellular locations.</dc:description>
  <dc:identifier>https://sonar.ch/global/documents/83840</dc:identifier>
  <dc:language>eng</dc:language>
  <dc:relation>info:eu-repo/semantics/altIdentifier/doi/10.1038/ncb2849</dc:relation>
  <dc:relation>info:eu-repo/semantics/altIdentifier/pmid/24084861</dc:relation>
  <dc:source>Nature cell biology. - 2013</dc:source>
  <dc:subject xmlns:ns1="xml" ns1:lang="en">Animals</dc:subject>
  <dc:subject xmlns:ns2="xml" ns2:lang="en">Humans</dc:subject>
  <dc:subject xmlns:ns3="xml" ns3:lang="en">Lysosomes</dc:subject>
  <dc:subject xmlns:ns4="xml" ns4:lang="en">Models, Biological</dc:subject>
  <dc:subject xmlns:ns5="xml" ns5:lang="en">Peroxisomes</dc:subject>
  <dc:subject xmlns:ns6="xml" ns6:lang="en">Protein Binding</dc:subject>
  <dc:subject xmlns:ns7="xml" ns7:lang="en">TOR Serine-Threonine Kinases</dc:subject>
  <dc:subject xmlns:ns8="xml" ns8:lang="en">Tuberous Sclerosis</dc:subject>
  <dc:title xmlns:ns9="xml" ns9:lang="en">TSC on the peroxisome controls mTORC1.</dc:title>
  <dc:type>http://purl.org/coar/resource_type/c_6501</dc:type>
</oai_dc:dc>