Ineichen C Glannon W Temel Y Baumann CR Sürücü O 2014 Since the translational research findings of Benabid and colleagues which partly led to their seminal paper regarding the treatment of mainly tremor-dominant Parkinson patients through thalamic high-frequency-stimulation (HFS) in 1987, we still struggle with identifying a satisfactory mechanistic explanation of the underlying principles of deep brain stimulation (DBS). Furthermore, the technological advance of DBS devices (electrodes and implantable pulse generators, IPG's) has shown a distinct lack of dynamic progression. In light of this we argue that it is time to leave the paleolithic age and enter hellenistic times: the device-manufacturing industry and the medical community together should put more emphasis on advancing the technology rather than resting on their laurels. application/pdf https://sonar.ch/global/documents/89056 eng info:eu-repo/semantics/altIdentifier/doi/10.3389/fnhum.2014.00730 info:eu-repo/semantics/altIdentifier/pmid/25278864 info:eu-repo/semantics/openAccess Frontiers in human neuroscience. - 2014 deep brain stimulation development ethics functional neurosurgery innovation stereotactic operation technology A critical reflection on the technological development of deep brain stimulation (DBS). http://purl.org/coar/resource_type/c_6501