Journal article
Postinduction video-mediastinoscopy is as accurate and safe as video-mediastinoscopy in patients without pretreatment for potentially operable non-small cell lung cancer.
- Lardinois D Division of Thoracic Surgery and Institute of Medical Oncology, Inselspital Bern, Bern, Switzerland. didier.lardinois@chi.usz.ch
- Schallberger A
- Betticher D
- Ris HB
- 2003-04-10
Published in:
- The Annals of thoracic surgery. - 2003
Adult
Aged
Aged, 80 and over
Carcinoma, Non-Small-Cell Lung
Chemotherapy, Adjuvant
Combined Modality Therapy
Female
Humans
Lung Neoplasms
Lymph Node Excision
Lymphatic Metastasis
Male
Mediastinoscopy
Middle Aged
Neoplasm Staging
Sensitivity and Specificity
Video Recording
English
BACKGROUND
Prospective assessment of accuracy and safety of video-mediastinoscopy (VMS) in patients without pretreatment and those after induction therapy for potentially operable non-small cell lung cancer.
METHODS
Between 1996 and 1999, 219 patients underwent VMS at our institution: 195 patients without pretreatment and 24 after completion of induction therapy. Mediastinal lymph nodes were dissected and biopsied according to the American Thoracic Society (ATS) lymph node mapping system using a video-assisted approach. The accuracy of VMS was assessed for each patient according to the results obtained from mediastinal lymph node dissection (MLND) performed during lung resection.
RESULTS
Video-mediastinoscopy in patients without pretreatment revealed a sensitivity, specificity, and accuracy as compared with MLND of 87%, 100%, and 95.6%, respectively, and a procedure-related complication rate of 4% (8/195 patients). Video-mediastinoscopy in patients after induction therapy revealed a sensitivity, specificity, and accuracy of 81%, 100%, and 91% as compared with MLND, without apparent complications.
CONCLUSIONS
Video-mediastinoscopy performed after induction therapy for non-small cell lung cancer is as accurate as mediastinoscopy in patients without pretreatment and did not confer additional morbidity.
Prospective assessment of accuracy and safety of video-mediastinoscopy (VMS) in patients without pretreatment and those after induction therapy for potentially operable non-small cell lung cancer.
METHODS
Between 1996 and 1999, 219 patients underwent VMS at our institution: 195 patients without pretreatment and 24 after completion of induction therapy. Mediastinal lymph nodes were dissected and biopsied according to the American Thoracic Society (ATS) lymph node mapping system using a video-assisted approach. The accuracy of VMS was assessed for each patient according to the results obtained from mediastinal lymph node dissection (MLND) performed during lung resection.
RESULTS
Video-mediastinoscopy in patients without pretreatment revealed a sensitivity, specificity, and accuracy as compared with MLND of 87%, 100%, and 95.6%, respectively, and a procedure-related complication rate of 4% (8/195 patients). Video-mediastinoscopy in patients after induction therapy revealed a sensitivity, specificity, and accuracy of 81%, 100%, and 91% as compared with MLND, without apparent complications.
CONCLUSIONS
Video-mediastinoscopy performed after induction therapy for non-small cell lung cancer is as accurate as mediastinoscopy in patients without pretreatment and did not confer additional morbidity.
- Language
-
- English
- Open access status
- closed
- Identifiers
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- DOI 10.1016/s0003-4975(02)04714-8
- PMID 12683545
- Persistent URL
- https://sonar.ch/global/documents/192142
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