Journal article
Basilar artery occlusion: Prognostic signs of severity on computed tomography.
- Poletti PA Service of Radiology, University Hospital of Geneva, Switzerland. Electronic address: pierre-alexandre.poletti@hcuge.ch.
- Pereira VM Service of Neuroradiology, University Hospital of Geneva, 4 rue Gabrielle-Perret-Gentil, 1211 Geneva, Switzerland; Department of Medical Imaging, University of Toronto, Canada; Department of Surgery, University of Toronto, Canada.
- Lovblad KO Service of Neuroradiology, University Hospital of Geneva, 4 rue Gabrielle-Perret-Gentil, 1211 Geneva, Switzerland.
- Canel L Service of Radiology, University Hospital of Geneva, Switzerland.
- Sztajzel R Service of Neurology, University Hospital of Geneva, 4 rue Gabrielle-Perret-Gentil, 1211 Geneva, Switzerland.
- Becker M Service of Radiology, University Hospital of Geneva, Switzerland.
- Perneger T Division of Clinical Epidemiology, University Hospital of Geneva, 4 rue Gabrielle-Perret-Gentil, 1211 Geneva, Switzerland.
- Platon A Service of Radiology, University Hospital of Geneva, Switzerland.
- 2015-04-11
Published in:
- European journal of radiology. - 2015
Basilar artery
Computed tomography
Occlusion
Aged
Arterial Occlusive Diseases
Basilar Artery
Female
Humans
Male
Middle Aged
Prognosis
Severity of Illness Index
Tomography, X-Ray Computed
English
PURPOSE
To determine the computed tomography (CT) signs that are predictive of the clinical outcome of basilar artery occlusion (BAO).
MATERIALS AND METHODS
The study population consisted in 37 patients (14 women, 23 men, mean age: 63 years), admitted with onset of neurological deficit, starting 1-72 h prior to admission, who were diagnosed with BAO on the basis of a CT examination with intravenous contrast agent. The following signs were collected on CT scans performed on admission: clot density on noncontrast images, clot length, and clot location, as well as the presence of acute ischemic lesions. The results were compared against the modified Rankin Scale (mRS) score of patients at 3 months, favorable clinical outcome being defined as a mRS score ≤3.
RESULTS
The clinical outcome was favorable in 13 (35%) of the 37 patients and unfavorable in 24 (65%). Signs of acute ischemia were visible in 13 of the 24 patients with unfavorable outcome but in none of the 13 patients with favorable outcome (p<0.001). None of the other CT signs analyzed were significantly correlated with clinical prognosis.
CONCLUSION
Of all the CT signs analyzed, only the presence of signs of acute ischemia on the admission CT of patients with BAO was associated with poor prognosis.
To determine the computed tomography (CT) signs that are predictive of the clinical outcome of basilar artery occlusion (BAO).
MATERIALS AND METHODS
The study population consisted in 37 patients (14 women, 23 men, mean age: 63 years), admitted with onset of neurological deficit, starting 1-72 h prior to admission, who were diagnosed with BAO on the basis of a CT examination with intravenous contrast agent. The following signs were collected on CT scans performed on admission: clot density on noncontrast images, clot length, and clot location, as well as the presence of acute ischemic lesions. The results were compared against the modified Rankin Scale (mRS) score of patients at 3 months, favorable clinical outcome being defined as a mRS score ≤3.
RESULTS
The clinical outcome was favorable in 13 (35%) of the 37 patients and unfavorable in 24 (65%). Signs of acute ischemia were visible in 13 of the 24 patients with unfavorable outcome but in none of the 13 patients with favorable outcome (p<0.001). None of the other CT signs analyzed were significantly correlated with clinical prognosis.
CONCLUSION
Of all the CT signs analyzed, only the presence of signs of acute ischemia on the admission CT of patients with BAO was associated with poor prognosis.
- Language
-
- English
- Open access status
- closed
- Identifiers
-
- DOI 10.1016/j.ejrad.2015.03.004
- PMID 25857713
- Persistent URL
- https://sonar.ch/global/documents/192287
Statistics
Document views: 16
File downloads: