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Standardized multilevel transition program: Does it affect renal transplant outcome?
Journal article

Standardized multilevel transition program: Does it affect renal transplant outcome?

  • Weitz M Nephrology Unit, University Children's Hospital Zurich, Zurich, Switzerland.
  • Heeringa S Department of Nephrology, University Hospital Zurich, Zurich, Switzerland.
  • Neuhaus TJ Children's Hospital Lucerne, Lucerne, Switzerland.
  • Fehr T Department of Nephrology, University Hospital Zurich, Zurich, Switzerland.
  • Laube GF Nephrology Unit, University Children's Hospital Zurich, Zurich, Switzerland.
  • 2015-08-12
Published in:
  • Pediatric transplantation. - 2015
acute rejection
adherence
glomerular filtration rate
non-adherence
transfer
transition
Adolescent
Adult
Female
Glomerular Filtration Rate
Graft Rejection
Humans
Kidney Transplantation
Male
Outcome and Process Assessment, Health Care
Postoperative Care
Regression Analysis
Retrospective Studies
Transition to Adult Care
Young Adult
English The transfer of renal transplant patients from pediatric to adult care is a crucial step with a high risk of subsequent graft loss. Therefore, the transition should be a thoroughly planned, well-designed and multidisciplinary process focused on the individual patient. Our pediatric nephrology department introduced a structured step-by-step transition program supported by a multidisciplinary team of health professionals. The purpose of our study was to determine the effects of the transition program on eGFR and number of ARs in comparison to a group without a transition program at one and three yr after transfer. We conducted a single-center retrospective cohort study of renal transplant patients prior to and after the introduction of the transition program. Multiple regression analysis revealed a significantly lower decline of eGFR in the group with transition program (-11.3 ± 44 mL/min/1.73 m(2) ) compared to the group without transition program (-28.4 ± 33 mL/min/1.73 m(2) ) at three yr after transfer. The number of AR episodes significantly decreased from 34.6% in the group without transition program to 9.1% in the group with transition program. The standardized multilevel transition program seems to have significant positive effects on eGFR and number of AR episodes in renal transplant patients.
Language
  • English
Open access status
closed
Identifiers
Persistent URL
https://sonar.ch/global/documents/235940
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