Journal article
Identification in mouse macrophages of a new 4Kb mRNA present in hematopoietic tissues, which shares a short nucleotide sequence with erythropoietin mRNA.
- Chicheportiche Y Department of Pathology, Centre Médical Universitaire, Geneva, Switzerland.
- Ody C
- Vassalli P
- 1995-04-26
Published in:
- Biochemical and biophysical research communications. - 1995
Anemia
Animals
Base Sequence
Blotting, Northern
Cells, Cultured
Cloning, Molecular
DNA Primers
Erythrocytes
Erythropoietin
Hematopoietic Stem Cells
Hybridomas
Macrophages, Peritoneal
Mice
Mice, Inbred BALB C
Molecular Sequence Data
Polymerase Chain Reaction
Promoter Regions, Genetic
RNA, Messenger
Reference Values
Restriction Mapping
English
A mRNA of larger size (4 Kb) than that of erythropoietin is found in hematopoietic tissues and macrophages after hybridization of Northern blots with an EPO cRNA probe. The cross-hybridizing fragment is located in the 3' untranslated region of the EPO mRNA. The level of this new mRNA is increased in anemic mice, which suggests that it might correspond to a molecule involved in erythropoietic regulation.
- Language
-
- English
- Open access status
- closed
- Identifiers
-
- DOI 10.1006/bbrc.1995.1607
- PMID 7733961
- Persistent URL
- https://sonar.ch/global/documents/284975
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