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Sequence-Based Synteny Analysis of Multiple Large Genomes.
Journal article

Sequence-Based Synteny Analysis of Multiple Large Genomes.

  • Doerr D School of Computer and Communication Sciences, EPFL, Lausanne, Switzerland.
  • Moret BME School of Computer and Communication Sciences, EPFL, Lausanne, Switzerland. Bernard.moret@epfl.ch.
  • 2017-12-27
Published in:
  • Methods in molecular biology (Clifton, N.J.). - 2018
Genome comparison
Large genomes
Marker sequences
Synteny analysis
Algorithms
Animals
Birds
Computational Biology
Genetic Markers
Genome
Genomics
Sequence Analysis, DNA
Software
Synteny
English Current methods for synteny analysis provide only limited support to study large genomes at the sequence level. In this chapter, we describe a pipeline based on existing tools that, applied in a suitable fashion, enables synteny analysis of large genomic datasets. We give a hands-on description of each step of the pipeline using four avian genomes for data. We also provide integration scripts that simplify the conversion and setup of data between the different tools in the pipeline.
Language
  • English
Open access status
closed
Identifiers
Persistent URL
https://sonar.ch/global/documents/99565
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