Detection of microembolic signals with transcranial Doppler ultrasound.

Georgiadis D; Siebler M

doi:10.1159/000092401

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Journal article

Detection of microembolic signals with transcranial Doppler ultrasound.

Georgiadis D Department of Neurology, University of Zürich, Zürich, Switzerland; Department of Neurology, University of Düsseldorf, Düsseldorf, Germany.
Siebler M

2007-02-10

Published in:

Frontiers of neurology and neuroscience. - 2006

Intracranial Embolism and Thrombosis

Ultrasonography, Doppler, Transcranial

English Detection of microembolic signals (MES) with transcranial Doppler was introduced in the late 1980s; several animal and in vitro models reported a high sensitivity and specificity with this technique. Monitoring for MES in various patient groups has provided valuable insights on stroke pathophysiology, although its clinical value remains a matter of debate. Diagnosis of imminent occlusion of the internal carotid artery following carotid endarterectomy, selection of high-risk patients with asymptomatic carotid disease, and evaluation of drug efficacy constitute potential applications of this technique.

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