Journal article
Flare-up reactions in severe drug hypersensitivity: infection or ongoing T-cell hyperresponsiveness.
- Jörg-Walther L Department of Rheumatology, Immunology and Allergology, Inselspital, University Hospital of Bern Bern, Switzerland.
- Schnyder B Department of Rheumatology, Immunology and Allergology, Inselspital, University Hospital of Bern Bern, Switzerland.
- Helbling A Department of Rheumatology, Immunology and Allergology, Inselspital, University Hospital of Bern Bern, Switzerland.
- Helsing K Department of Visceral Surgery and Medicine, Inselspital, University Hospital of Bern Bern, Switzerland.
- Schüller A Department of Visceral Surgery and Medicine, Inselspital, University Hospital of Bern Bern, Switzerland.
- Wochner A Department of Visceral Surgery and Medicine, Inselspital, University Hospital of Bern Bern, Switzerland.
- Pichler W ADR-AC GmbH, Adverse Drug Reactions, Analysis and Consulting Bern, Switzerland.
- 2015-10-29
Published in:
- Clinical case reports. - 2015
Drug hypersensitivity
T cell
drug rash with eosinophilia and systemic symptoms (DRESS)
flare-up reaction
infection
relapse
English
"Flare-up" reactions are late manifestations of severe T-cell-mediated drug hypersensitivity reactions. Management is anti-inflammatory treatment and avoiding unnecessary medicines. Symptoms like fever, lymph node swelling, and blood count abnormalities may lead to confusion with bacterial infections. For prompt recognition it is important to keep the differential diagnosis in mind.
- Language
-
- English
- Open access status
- gold
- Identifiers
-
- DOI 10.1002/ccr3.346
- PMID 26509009
- Persistent URL
- https://sonar.ch/global/documents/109
Statistics
Document views: 38
File downloads: