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Iridoid glycosides of Leonurus persicus.
Journal article

Iridoid glycosides of Leonurus persicus.

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  • 1999-07-08
Published in:
  • Journal of natural products. - 1999
Anti-Bacterial Agents
Anti-Infective Agents
Crystallography, X-Ray
Fungi
Glycosides
Gram-Negative Bacteria
Gram-Positive Bacteria
Lamiaceae
Magnetic Resonance Spectroscopy
Microbial Sensitivity Tests
Molecular Conformation
Spectrophotometry, Ultraviolet
Stereoisomerism
Turkey
English Two new iridoid glucosides, 6-O-acetylajugol (1) and 7, 8-epoxy-8-epi-loganic acid (2), together with five known iridoid glucosides, galiridoside (3), ajugoside (4), 10-deoxygeniposidic acid (5), 7-deoxy-8-epi-loganic acid (6), and 8-O-acetylharpagide (7), have been isolated from the aerial parts of Leonurus persicus. Leucosceptoside A (8), eugenyl beta-rutinoside (9), and kaempferol 3-O-glucoside (10) were also isolated. The structures of 1 and 2 were elucidated by extensive 1D- and 2D-NMR spectroscopy and molecular modeling. The structure of 3 was confirmed by single-crystal X-ray diffraction. Antimicrobial activity of compounds (1-10) was also evaluated against a panel of gram-positive and gram-negative bacteria and two strains of fungi.
Language
  • English
Open access status
closed
Identifiers
Persistent URL
https://sonar.ch/global/documents/111431
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