Journal article

Aging and drug discovery.

  • Bakula D Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark.
  • Aliper AM Pharmaceutical Artificial Intelligence Department, Insilico Medicine, Inc., Baltimore, MD 20850, USA.
  • Mamoshina P Pharmaceutical Artificial Intelligence Department, Insilico Medicine, Inc., Baltimore, MD 20850, USA.
  • Petr MA Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark.
  • Teklu A Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark.
  • Baur JA Institute for Diabetes, Obesity and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Campisi J Buck Institute for Research on Aging, Novato, CA 94945, USA.
  • Ewald CY Institute of Translational Medicine, Department of Health Sciences and Technology, Swiss Federal Institute for Technology (ETH) Zürich, Switzerland.
  • Georgievskaya A Youth Laboratories, Moscow, Russia.
  • Gladyshev VN Division of Genetics, Department of Medicine, Harvard Medical School, Brigham and Women's Hospital, Boston, MA 02115, USA.
  • Kovalchuk O Department of Biological Sciences, University of Lethbridge, Lethbridge, Alberta, Canada.
  • Lamming DW Department of Medicine, University of Wisconsin-Madison, Madison, WI 53706, USA.
  • Luijsterburg MS Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands.
  • Martín-Montalvo A Pancreatic Islet Development and Regeneration Unit/Laboratory of Aging Biology, Centro Andaluz de Biología Molecular y Medicina Regenerativa-CABIMER, Universidad de Sevilla-CSIC-Universidad Pablo de Olavide, Seville, Spain.
  • Maudsley S Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.
  • Mkrtchyan GV Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark.
  • Moskalev A Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
  • Olshansky SJ Division of Epidemiology and Biostatistics University of Illinois at Chicago School of Public Health, Chicago, IL 60612, USA.
  • Ozerov IV Pharmaceutical Artificial Intelligence Department, Insilico Medicine, Inc., Baltimore, MD 20850, USA.
  • Pickett A Juvenescence Limited, Douglas, Isle of Man, UK.
  • Ristow M Institute of Translational Medicine, Department of Health Sciences and Technology, Swiss Federal Institute for Technology (ETH) Zürich, Switzerland.
  • Zhavoronkov A Pharmaceutical Artificial Intelligence Department, Insilico Medicine, Inc., Baltimore, MD 20850, USA.
  • Scheibye-Knudsen M Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark.
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  • 2018-11-15
Published in:
  • Aging. - 2018
English Multiple interventions in the aging process have been discovered to extend the healthspan of model organisms. Both industry and academia are therefore exploring possible transformative molecules that target aging and age-associated diseases. In this overview, we summarize the presented talks and discussion points of the 5th Annual Aging and Drug Discovery Forum 2018 in Basel, Switzerland. Here academia and industry came together, to discuss the latest progress and issues in aging research. The meeting covered talks about the mechanistic cause of aging, how longevity signatures may be highly conserved, emerging biomarkers of aging, possible interventions in the aging process and the use of artificial intelligence for aging research and drug discovery. Importantly, a consensus is emerging both in industry and academia, that molecules able to intervene in the aging process may contain the potential to transform both societies and healthcare.
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  • English
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green
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https://sonar.ch/global/documents/113894
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