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Thermal model for optimization of vascular laser tissue soldering.
Journal article

Thermal model for optimization of vascular laser tissue soldering.

  • 2010-03-03
Published in:
  • Journal of biophotonics. - 2010
Absorption
Algorithms
Animals
Aorta
Blood Vessels
Calibration
Computer Simulation
Finite Element Analysis
In Vitro Techniques
Laser Therapy
Models, Biological
Rabbits
Temperature
Time Factors
Water
English Laser tissue soldering (LTS) is a promising technique for tissue fusion based on a heat-denaturation process of proteins. Thermal damage of the fused tissue during the laser procedure has always been an important and challenging problem. Particularly in LTS of arterial blood vessels strong heating of the endothelium should be avoided to minimize the risk of thrombosis. A precise knowledge of the temperature distribution within the vessel wall during laser irradiation is inevitable. The authors developed a finite element model (FEM) to simulate the temperature distribution within blood vessels during LTS. Temperature measurements were used to verify and calibrate the model. Different parameters such as laser power, solder absorption coefficient, thickness of the solder layer, cooling of the vessel and continuous vs. pulsed energy deposition were tested to elucidate their impact on the temperature distribution within the soldering joint in order to reduce the amount of further animal experiments. A pulsed irradiation with high laser power and high absorbing solder yields the best results.
Language
  • English
Open access status
closed
Identifiers
Persistent URL
https://sonar.ch/global/documents/115176
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