Variability of SCCmec in the Zurich area.
- Ender M Institute of Medical Microbiology, University of Zurich, Gloriastrasse 32, 8006, Zurich, Switzerland.
- Burger S
- Sokoli A
- Zbinden R
- Berger-Bächi B
- Heusser R
- Senn MM
- McCallum N
- 2008-11-27
Published in:
- European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology. - 2009
Bacterial Typing Techniques
DNA Fingerprinting
DNA, Bacterial
Genes, Bacterial
Genotype
Humans
Methicillin-Resistant Staphylococcus aureus
Microbial Sensitivity Tests
Molecular Epidemiology
Polymorphism, Genetic
Prevalence
Staphylococcal Infections
Switzerland
English
A periodic survey of methicillin-resistant Staphylococcus aureus (MRSA) in Zurich in 2004 and 2006 revealed a consistently low prevalence of MRSA. SCCmec and ccr typing showed fluctuations in the proportions of SCCmec types and in the carriage of mobile virulence determinants. Together with the presence of variant SCCmecs these findings suggest a high clonal diversity and level of SCCmec recombination. The prevalence of a local "drug clone", associated with low-level methicillin resistance and rapid growth, significantly decreased. This clone had spread among intraveneous drug users, steadily increasing from 1994 to 2001 and was dominant in 2001. Apparently, changes in the management of the Zurich drug scene have restricted the spread of this clone.
- Language
-
- English
- Open access status
- green
- Identifiers
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- DOI 10.1007/s10096-008-0663-7
- PMID 19034542
- Persistent URL
- https://sonar.ch/global/documents/119268
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