Journal article
Asymmetric conjugate addition reactions of Meldrum's acid derived acceptors employing chiral phosphoramidite ligands.
- Watanabe T Laboratorium für Organische Chemie, ETH-Hönggerberg HCI H335, CH-8093 Zürich, Switzerland.
- Knöpfel TF
- Carreira EM
- 2003-11-25
Published in:
- Organic letters. - 2003
English
[reaction: see text] The enantioselective conjugate addition reaction of Et(2)Zn to Meldrum's acid derived acceptors, mediated by a catalyst formed from Cu(O(2)CCF(3))(2) and a phosphoramidite ligand, is reported. Adducts are obtained in useful yields and up to 94% ee.
- Language
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- English
- Open access status
- closed
- Identifiers
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- DOI 10.1021/ol035575q
- PMID 14627382
- Persistent URL
- https://sonar.ch/global/documents/123475
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