Clinical significance of interleukin-2/gamma interferon ratios in Mycobacterium tuberculosis-specific T-cell signatures.
- Suter-Riniker F University of Bern, Institute for Infectious Diseases, Friedbühlstrasse 51, 3010 Bern, Switzerland. franziska.suter@ifik.unibe.ch
- Berger A
- Mayor D
- Bittel P
- Iseli P
- Bodmer T
- 2011-06-03
Published in:
- Clinical and vaccine immunology : CVI. - 2011
English
The simultaneous determination of interleukin-2 (IL-2) and gamma interferon (IFN-γ) in QuantiFERON-TB test plasma supernatants permitted the detection of shifts in Mycobacterium tuberculosis-specific T-cell signatures. A subset of the 84 subjects tested revealed a significantly elevated IL-2/IFN-γ ratio, which may be a marker for the successful elimination of M. tuberculosis infection.
- Language
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- English
- Open access status
- gold
- Identifiers
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- DOI 10.1128/CVI.05013-11
- PMID 21632888
- Persistent URL
- https://sonar.ch/global/documents/1241
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