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Active immunotherapy for chronic diseases.
Journal article

Active immunotherapy for chronic diseases.

  • Bachmann MF University Hospital Zurich, Dermatology, Gloriastr 31, 8091 Zurich, Switzerland. martin.bachmann@me.com
  • Whitehead P
  • 2013-02-19
Published in:
  • Vaccine. - 2013
Antibodies, Monoclonal
Chronic Disease
Humans
Immunization, Passive
Immunotherapy, Active
Patient Compliance
Treatment Failure
English With the effective control of infectious diseases in many parts of the world, chronic, non-communicable diseases have become the major cause of death and disability. Monoclonal antibodies (mAbs) have become an important class of drugs for the treatment of such diseases. Nevertheless, mAbs suffer from major shortcomings in a chronic setting: most notably, generation of anti-antibodies and high cost of goods. Here, we discuss a novel approach to treat chronic diseases based on active rather than passive immunization and contrast the 2 treatment modalities to highlight their respective advantages and disadvantages.
Language
  • English
Open access status
closed
Identifiers
Persistent URL
https://sonar.ch/global/documents/12790
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