Journal article
"Exercise induced asthma" is not always asthma.
- Kofler T Department of Pneumology, University Hospital Basel, Switzerland.
- Daikeler T Rheumatology Division, University Hospital Basel, Basel, Switzerland.
- Savic Prince S Institute of Pathology, University Hospital Basel, Switzerland.
- Holzmann Y Department of Nephrology and Transplantational Medicine, University Hospital Basel, Switzerland.
- Bremerich J Department of Cardiothorac Radiology, University Hospital Basel, Switzerland.
- Tamm M Department of Pneumology, University Hospital Basel, Switzerland.
- Jahn K Department of Pneumology, University Hospital Basel, Switzerland.
- 2018-07-07
Published in:
- Respiratory medicine case reports. - 2018
English
A 25 year old woman was referred to our center for further evaluation of an exercise-induced dyspnea. Moreover, the patient suffered from hoarseness and recurrent sinusitis and otitis. After initially finding nothing suspicious, a spiro-ergometry was performed. Interestingly, we saw a relevant limitation of the inspiratory flow-volume curve under maximal exercise load. Further evaluation (in particular the bronchoscopy and the resulting biopsies) led us to the final diagnosis of a granulomatosis with polyangiitis. After 4 weeks of an established therapy regime with prednisone and rituximab the prior detected subglottic stenosis and the inspiratory flow-volume curve limitation could no longer detected. We describe a rare differential diagnosis of an exercise-induced asthma and we underline the importance of a multimodal therapy concept. We highlight the critical nature of the flow-volume curve in spiro-ergometry under maximal exercise load. We recommend frequent follow-up control visits to monitor the subglottic stenosis.
- Language
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- English
- Open access status
- gold
- Identifiers
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- DOI 10.1016/j.rmcr.2018.05.015
- PMID 29977782
- Persistent URL
- https://sonar.ch/global/documents/130296
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