Journal article
The influence of an anti-inflammatory diet on gingivitis. A randomized controlled trial.
- Woelber JP Department of Operative Dentistry and Periodontology, Faculty of Medicine, Medical Center, University of Freiburg, Freiburg, Germany.
- Gärtner M Department of Operative Dentistry and Periodontology, Faculty of Medicine, Medical Center, University of Freiburg, Freiburg, Germany.
- Breuninger L Department of Operative Dentistry and Periodontology, Faculty of Medicine, Medical Center, University of Freiburg, Freiburg, Germany.
- Anderson A Department of Operative Dentistry and Periodontology, Faculty of Medicine, Medical Center, University of Freiburg, Freiburg, Germany.
- König D Institute of Sports and Sports Science, Faculty of Medicine, Medical Center, University of Freiburg, Freiburg, Germany.
- Hellwig E Department of Operative Dentistry and Periodontology, Faculty of Medicine, Medical Center, University of Freiburg, Freiburg, Germany.
- Al-Ahmad A Department of Operative Dentistry and Periodontology, Faculty of Medicine, Medical Center, University of Freiburg, Freiburg, Germany.
- Vach K Department of Medical Biometry and Statistics, Faculty of Medicine, Medical Center, University of Freiburg, Freiburg, Germany.
- Dötsch A Department of Physiology and Biochemistry of Nutrition, Max Rubner-Institut, Karlsruhe, Germany.
- Ratka-Krüger P Department of Operative Dentistry and Periodontology, Faculty of Medicine, Medical Center, University of Freiburg, Freiburg, Germany.
- Tennert C Department of Restorative, Preventive and Pediatric Dentistry, University of Berne, Berne, Switzerland.
- 2019-04-04
Published in:
- Journal of clinical periodontology. - 2019
carbohydrates
host modulation
micronutrients
nutrition
omega-3 fatty acids
periodontal disease
Anti-Inflammatory Agents
Dental Plaque Index
Diet
Gingivitis
Humans
Periodontal Index
English
AIM
Aim of this study was to investigate the influence of an anti-inflammatory diet on different parameters in patients with gingivitis.
MATERIALS AND METHODS
Thirty patients were randomly allocated to an experimental and a control group stratified by their plaque values. The experimental group had to change to a diet low in processed carbohydrates and animal proteins, and rich in omega-3 fatty acids, vitamin C, vitamin D, antioxidants, plant nitrates and fibres for 4 weeks. The control group did not change their diet. Both groups suspended interdental cleaning. Periodontal parameters were assessed by a blinded dentist. Serological and subgingival plaque samples were taken at baseline and end.
RESULTS
While there were no differences regarding the plaque values, the experimental group showed a significant reduction in gingival bleeding (GI Baseline: 1.04 ± 0.21, GI End: 0.61 ± 0.29, p < 0.05), a significant increase in Vitamin D values and a significant weight loss. There were no inter-group differences regarding the inflammatory serological parameters, the serological omega fatty acids, nor the subgingival microbiome composition.
CONCLUSION
The evaluated diet could significantly reduce gingivitis in a clinically relevant range, while serological inflammatory parameters and the subgingival microbiome seem to be unaffected in this study duration. (German Clinical Trials Register; DRKS00009888).
Aim of this study was to investigate the influence of an anti-inflammatory diet on different parameters in patients with gingivitis.
MATERIALS AND METHODS
Thirty patients were randomly allocated to an experimental and a control group stratified by their plaque values. The experimental group had to change to a diet low in processed carbohydrates and animal proteins, and rich in omega-3 fatty acids, vitamin C, vitamin D, antioxidants, plant nitrates and fibres for 4 weeks. The control group did not change their diet. Both groups suspended interdental cleaning. Periodontal parameters were assessed by a blinded dentist. Serological and subgingival plaque samples were taken at baseline and end.
RESULTS
While there were no differences regarding the plaque values, the experimental group showed a significant reduction in gingival bleeding (GI Baseline: 1.04 ± 0.21, GI End: 0.61 ± 0.29, p < 0.05), a significant increase in Vitamin D values and a significant weight loss. There were no inter-group differences regarding the inflammatory serological parameters, the serological omega fatty acids, nor the subgingival microbiome composition.
CONCLUSION
The evaluated diet could significantly reduce gingivitis in a clinically relevant range, while serological inflammatory parameters and the subgingival microbiome seem to be unaffected in this study duration. (German Clinical Trials Register; DRKS00009888).
- Language
-
- English
- Open access status
- closed
- Identifiers
-
- DOI 10.1111/jcpe.13094
- PMID 30941800
- Persistent URL
- https://sonar.ch/global/documents/131931
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