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Patterning of skeletal muscle.
Journal article

Patterning of skeletal muscle.

  • Arber S Department of Cell Biology, Biozentrum, Klingelbergstrasse 70, University of Basel, CH-4056 Basel, Switzerland. silvia.arber@unibas.ch
  • Burden SJ
  • Harris AJ
  • 2002-02-28
Published in:
  • Current opinion in neurobiology. - 2002
Animals
Cell Lineage
Motor Neurons
Muscle Fibers, Skeletal
Muscle, Skeletal
English Recent studies challenge the view that signals provided by motor neurons are required to activate subsynaptic nuclei and induce postsynaptic specializations in developing skeletal muscle. New findings show that acetylcholine receptor genes are expressed and that acetylcholine receptor clusters form preferentially in the prospective synaptic region of muscle independently of motor innervation. These results indicate that developing myotubes are patterned by mechanisms intrinsic to developing muscles and raise the possibility that patterning of muscles may influence the growth pattern of motor axons and the sites where synapses form.
Language
  • English
Open access status
closed
Identifiers
Persistent URL
https://sonar.ch/global/documents/137516
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