Outbreak caused by NDM-1- and RmtB-producing Escherichia coli in Bulgaria.
- Poirel L Medical and Molecular Microbiology Unit, Department of Medicine, Faculty of Science, University of Fribourg, Fribourg, Switzerland.
- Savov E
- Nazli A
- Trifonova A
- Todorova I
- Gergova I
- Nordmann P
- 2014-02-12
Published in:
- Antimicrobial agents and chemotherapy. - 2014
English
Twelve consecutive carbapenem-resistant Escherichia coli isolates were recovered from patients (infection or colonization) hospitalized between March and September 2012 in different units at a hospital in Bulgaria. They all produced the carbapenemase NDM-1 and the extended-spectrum-β-lactamase CTX-M-15, together with the 16S rRNA methylase RmtB, conferring high-level resistance to all aminoglycosides. All those isolates were clonally related and belonged to the same sequence type, ST101. In addition to being the first to identify NDM-producing isolates in Bulgaria, this is the very first study reporting an outbreak of NDM-1-producing E. coli in the world.
- Language
-
- English
- Open access status
- bronze
- Identifiers
-
- DOI 10.1128/AAC.02571-13
- PMID 24514099
- Persistent URL
- https://sonar.ch/global/documents/138843
Statistics
Document views: 36
File downloads:
- Full-text: 0