In vitro dosimetry of agglomerates.
- Hirsch V Adolphe Merkle Institute, University of Fribourg, Route de l'Ancienne Papeterie, P.O. Box 209, Marly 1723, Switzerland.
- Kinnear C
- Rodriguez-Lorenzo L
- Monnier CA
- Rothen-Rutishauser B
- Balog S
- Petri-Fink A
- 2014-05-24
Published in:
- Nanoscale. - 2014
Cell Survival
Gold
HeLa Cells
Humans
Hydrogen-Ion Concentration
Light
Metal Nanoparticles
Polyvinyl Alcohol
Scattering, Radiation
Tiopronin
English
Agglomeration of nanoparticles in biological fluids is a pervasive phenomenon that leads to difficulty in the interpretation of results from in vitro exposure, primarily due to differing particokinetics of agglomerates to nanoparticles. Therefore, well-defined small agglomerates were designed that possessed different particokinetic profiles, and their cellular uptake was compared to a computational model of dosimetry. The approach used here paves the way for a better understanding of the impact of agglomeration on the nanoparticle-cell interaction.
- Language
-
- English
- Open access status
- green
- Identifiers
-
- DOI 10.1039/c4nr00460d
- PMID 24853436
- Persistent URL
- https://sonar.ch/global/documents/138847
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