NDEL1-PDGFRB fusion gene in a myeloid malignancy with eosinophilia associated with resistance to tyrosine kinase inhibitors.

• Byrgazov K Children's Cancer Research Institute, Vienna, Austria.
• Kastner R Children's Cancer Research Institute, Vienna, Austria.
• Gorna M CeMM, Research Center for Molecular Medicine of the Austrian Academy of Science, Vienna, Austria.
• Hoermann G Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria.
• Koenig M Children's Cancer Research Institute, Vienna, Austria.
• Lucini CB Children's Cancer Research Institute, Vienna, Austria.
• Ulreich R Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.
• Benesch M Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.
• Strenger V Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.
• Lackner H Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.
• Schwinger W Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.
• Sovinz P Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.
• Haas OA Children's Cancer Research Institute, Vienna, Austria.
• van den Heuvel-Eibrink M Department of Pediatric Hemato-Oncology, Erasmus MC-Sophia Children's Hospital, Rotterdam, The Netherlands.
• Niemeyer CM Department of Pediatrics and Adolescent Medicine, University of Freiburg, Freiburg, Germany.
• Hantschel O Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
• Valent P Division of Hematology and Hemostaseology, Department of Internal Medicine, Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, Vienna, Austria.
• Superti-Furga G CeMM, Research Center for Molecular Medicine of the Austrian Academy of Science, Vienna, Austria.
• Urban C Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.
• Dworzak MN Children's Cancer Research Institute, Vienna, Austria.
• Lion T Children's Cancer Research Institute, Vienna, Austria.

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Animals

Carrier Proteins

Cell Line

Drug Resistance, Neoplasm

Eosinophilia

Humans

Infant

Mice

Mutation

Myeloproliferative Disorders

Oncogene Proteins, Fusion

Protein Conformation

Protein Kinase Inhibitors

Protein-Tyrosine Kinases

Receptor, Platelet-Derived Growth Factor beta

Sequence Analysis, DNA

Transduction, Genetic