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Progression of cardiovascular risk factors in black Africans: 3 year follow up of the SABPA cohort study.
Journal article

Progression of cardiovascular risk factors in black Africans: 3 year follow up of the SABPA cohort study.

  • Hamer M Department of Epidemiology and Public Health, University College London, London, UK; Hypertension in Africa Research Team, School for Physiology, Nutrition and Consumer Sciences, North-West University, Potchefstroom, South Africa. Electronic address: m.hamer@ucl.ac.uk.
  • von Känel R Department of Neurology, Inselspital, Bern University Hospital and University of Bern, Switzerland.
  • Reimann M Autonomic and Neuroendocrinological Laboratory Dresden, Department of Neurology, University Hospital Carl Gustav Carus, Dresden University of Technology, Dresden, Germany.
  • Malan NT Hypertension in Africa Research Team, School for Physiology, Nutrition and Consumer Sciences, North-West University, Potchefstroom, South Africa.
  • Schutte AE Hypertension in Africa Research Team, School for Physiology, Nutrition and Consumer Sciences, North-West University, Potchefstroom, South Africa.
  • Huisman HW Hypertension in Africa Research Team, School for Physiology, Nutrition and Consumer Sciences, North-West University, Potchefstroom, South Africa.
  • Malan L Hypertension in Africa Research Team, School for Physiology, Nutrition and Consumer Sciences, North-West University, Potchefstroom, South Africa.
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  • 2014-12-02
Published in:
  • Atherosclerosis. - 2015
Biomarkers
Black African
Cardiovascular disease
Epidemiology
Adult
African Continental Ancestry Group
Blood Glucose
Cardiovascular Diseases
Cholesterol
Cohort Studies
Diastole
Disease Progression
Female
Fibrin Fibrinogen Degradation Products
Fibrinogen
Humans
Male
Middle Aged
Risk Factors
South Africa
Systole
Waist Circumference
English Recent work identified a high prevalence of modifiable risk factors for cardiovascular disease (CVD) among urban black South Africans. The aim was to track the progression of CVD risk factors in a multi-ethnic sample of South Africans. Participants were 173 black (aged 47.5 ± 7.8 yrs) and 186 white teachers (aged 49.6 ± 9.9 yrs) that were examined at baseline and 3 years follow-up. Blacks demonstrated a substantially higher prevalence of composite CVD burden (defined as history of physician diagnosed heart disease, use of anti-hypertensives, anti-diabetic, or statin medications at either time point) compared to whites (49.1 vs. 32.0%, p = 0.012) respectively. After controlling for baseline, the black participants demonstrated greater increases in 24 h systolic and diastolic blood pressure, total cholesterol, fasting glucose, fibrinogen, D-dimer, and waist circumference in comparison with whites. In summary, an adverse progression of CVD risk factors was observed in the whole sample, although to a larger degree in black participants. Aggressive treatment strategies for controlling risk factors in black Africans are needed to reduce the increasing burden of CVD in South Africa.
Language
  • English
Open access status
hybrid
Identifiers
Persistent URL
https://sonar.ch/global/documents/138958
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