Back
Prolonged remission induced by cyclosporine in a patient with familial thrombocytopenia and enteropathy.
Journal article

Prolonged remission induced by cyclosporine in a patient with familial thrombocytopenia and enteropathy.

  • 1995-05-01
Published in:
  • Pediatric hematology and oncology. - 1995
Adult
Autoimmune Diseases
Common Variable Immunodeficiency
Cyclosporine
Humans
Intestinal Diseases
Male
Thrombocytopenia
English A 21-year-old patient, since the age of 16, presented a familial type of chronic autoimmune thrombocytopenia that responded only partially to various types of immunosuppressive treatment. His prolonged survival, compared to his decreased siblings, was complicated by the appearance of a severe enteropathy. High doses of corticosteroids induced a type 1 diabetes as a major side effect. The introduction of cyclosporine resulted in both a continuous complete clinical remission and a partial hematological remission and allowed the discontinuation of all other medication for 18 months. In uncommon complex autoimmune disease, cyclosporine may represent a safe and effective alternate therapy when other immunosuppressive agents have failed.
Language
  • English
Open access status
closed
Identifiers
Persistent URL
https://sonar.ch/global/documents/139055
Statistics
Document views: 49 File downloads: