Mathematical models of sleep regulation.
- Achermann P Institute of Pharmacology and Toxicology, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland. acherman@pharma.unizh.ch
- Borbély AA
- 2003-04-18
Published in:
- Frontiers in bioscience : a journal and virtual library. - 2003
English
The level of EEG slow-wave activity (SWA) is determined by the duration of prior sleep and waking. SWA is a marker of nonREM sleep intensity and may serve as an indicator of sleep homeostasis. The two-process model of sleep regulation posits the interaction of the homeostatic Process S and the circadian Process C. Also models of neurobehavioral functions (three-process model; interactive models of alertness and cognitive throughput) are based on the concept of an interaction between homeostatic and circadian factors. Whether the interaction is linear or non-linear is still unresolved. Models may serve as a guiding principle for specifying the relationship between processes occurring at the macroscopic and microscopic level of analysis.
- Language
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- English
- Open access status
- green
- Identifiers
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- DOI 10.2741/1064
- PMID 12700054
- Persistent URL
- https://sonar.ch/global/documents/14038
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