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Journal article

LC3-associated phagocytosis.

  • Romao S Viral Immunobiology; Institute of Experimental Immunology; University of Zürich; Zürich, Switzerland.
  • Münz C Viral Immunobiology; Institute of Experimental Immunology; University of Zürich; Zürich, Switzerland.
  • 2014-01-14
Published in:
  • Autophagy. - 2014
Atg8/LC3
MHC class II
macroautophagy
phagocytosis
phagosomal maturation
Adaptor Proteins, Signal Transducing
Animals
Antigen Presentation
Autophagy
Histocompatibility Antigens Class II
Humans
Microtubule-Associated Proteins
Phagosomes
English A recent report from our group has described that upon engulfment of pathogens, a subset of phagosomes is formed to preserve antigens for prolonged presentation on MHC class II molecules. The distinctive feature of these particular vesicles is their coating with LC3/Atg8, a key component of the autophagy machinery. Here we discuss the possible outcomes of LC3-associated phagocytosis and its implications in the context of immunity.
Language
  • English
Open access status
bronze
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Persistent URL
https://sonar.ch/global/documents/142072
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