Journal article
Parasite immune evasion: a momentous molecular war.
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Schmid-Hempel P
ETH Zürich, Institute of Integrative Biology , Universitätsstrasse 16 CH-8092 Zürich, Switzerland. psh@env.ethz.ch
Published in:
- Trends in ecology & evolution. - 2008
English
Current research in immunology shows that parasite evasion of host immunity is ubiquitous and involves a wide range of molecular mechanisms. Furthermore, immune evasion appears to generate a large spectrum of pathogenic effects, such as cytokine storms and inflammation. Understanding the relationships between the beneficial effects of immune evasion and its pathogenic consequences therefore provides a new framework to reassess many of the core questions of the evolutionary ecology of host-parasite interactions, such as the evolution of virulence, immune defence strategies, infective dose and host specificity, and to address questions that thus far could not be satisfactorily analysed.
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Language
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Open access status
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closed
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Identifiers
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Persistent URL
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https://sonar.ch/global/documents/142664
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