Journal article
Incorporation of penicillin-producing fungi into living materials to provide chemically active and antibiotic-releasing surfaces.
- Gerber LC Department of Chemistry and Applied Biosciences, ETH Zurich, Switzerland.
- Koehler FM
- Grass RN
- Stark WJ
- 2012-10-10
Published in:
- Angewandte Chemie (International ed. in English). - 2012
English
Living materials: artificial biological niches are loaded with the penicillin-producing mold Penicillium chrysogenum. This living material consumes food through a nanoporous top layer and releases the antibiotic on-site. No reloading of the active compound is needed. Gram-positive bacteria were efficiently killed if nearby, whereas Gram-negative bacteria (control experiment, not sensitive to penicillin) were not affected.
- Language
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- English
- Open access status
- closed
- Identifiers
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- DOI 10.1002/anie.201204337
- PMID 23044633
- Persistent URL
- https://sonar.ch/global/documents/143389
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