Back
Jejunal Occlusion Caused by Heterotopic Gastric and Duodenal Mucosa: A Late Complication of a Complex Intestinal Malformation.
Journal article

Jejunal Occlusion Caused by Heterotopic Gastric and Duodenal Mucosa: A Late Complication of a Complex Intestinal Malformation.

  • Seyde O 1 Geneva University Hospitals, Switzerland.
  • Puppa G 1 Geneva University Hospitals, Switzerland.
  • Morel P 1 Geneva University Hospitals, Switzerland.
  • Wildhaber BE 1 Geneva University Hospitals, Switzerland.
  • Rougemont AL 1 Geneva University Hospitals, Switzerland.
  • 2017-04-07
Published in:
  • International journal of surgical pathology. - 2017
ectopia
gastrointestinal tract duplication
intestinal atresia
β-catenin
Abdominal Pain
Adult
Anastomosis, Surgical
Choristoma
DNA Mutational Analysis
Duodenum
Enterostomy
Exons
Female
Gastric Mucosa
Humans
Infant, Premature
Intestinal Atresia
Intestinal Mucosa
Intestinal Obstruction
Jejunum
Mutation
Stomach Diseases
Vomiting
Wnt Proteins
Wnt Signaling Pathway
Young Adult
beta Catenin
English We report a rare case of late complication of a complex intestinal malformation. At day 1 of life, a baby girl underwent resection of an atretic jejunal segment, associated with an enteric duplication harboring foci of gastric and duodenal heterotopia. After an asymptomatic period of 19 years, the patient presented with acute bowel obstruction. Recurrence of the jejunal occlusion at the previous anastomotic site was caused by mucosa hyperplasia in association with heterotopic gastric and duodenal tissue. A Wnt/β-catenin pathway deregulation was hypothesized but not confirmed by CTNNB1 exon 3 mutation analysis. This case illustrates a rare association of 3 pathologies-namely, intestinal atresia, enteric duplication, and heterotopia, with a late-occurring acute complication.
Language
  • English
Open access status
closed
Identifiers
Persistent URL
https://sonar.ch/global/documents/144815
Statistics
Document views: 20 File downloads: