Collagen of Dupuytren's Disease
- Bailey, A. J. Agricultural Research Council Meat Research Institute, Langford, Bristol, U.K.
- Sims, T. J. Agricultural Research Council Meat Research Institute, Langford, Bristol, U.K.
- Gabbiani, G. Department of Pathology, University of Geneva, Geneva, Switzerland.
- Bazin, S. Unité de Recherches de Génétique Médicale, Hopital des Enfants Malades, Paris, France.
- Lelous, M. Unité de Recherches de Génétique Médicale, Hopital des Enfants Malades, Paris, France.
Published in:
- Clinical Science. - Portland Press Ltd.. - 1977, vol. 53, no. 5, p. 499-502
English
1. In contrast to collagen from the aponeurosis of normal adult subjects, the nodules, contractures and apparently unaffected aponeurosis from patients with Dupuytren's disease contained substantial amounts of type III collagen.
2. The presence of type III collagen supports the previous proposal that the initial response to injury is the synthesis of an increased proportion of this form of collagen. The increased amounts in the apparently unaffected aponeurosis indicate the disease is not strictly focal but more systemic than is usually considered.
- Language
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- English
- Open access status
- green
- Identifiers
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- DOI 10.1042/cs0530499
- ISSN 0301-0538
- Persistent URL
- https://sonar.ch/global/documents/144861
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