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Inhibitory cytokines and cytokine inhibitors.
Journal article

Inhibitory cytokines and cytokine inhibitors.

  • Burger D Department of Medicine, University Hospital, Geneva, Switzerland.
  • Dayer JM
  • 1995-06-01
Published in:
  • Neurology. - 1995
Cytokines
Humans
Inflammation Mediators
Interleukin 1 Receptor Antagonist Protein
Interleukin-1
Interleukin-10
Interleukin-4
Receptors, Interleukin-1
Receptors, Tumor Necrosis Factor
Sialoglycoproteins
Tumor Necrosis Factor-alpha
English Cytokines such as interleukin-1 and tumor necrosis factor are involved in the triggering of the immune response, induction of acute inflammatory events, and transition to, or persistence of, chronic inflammation. The action of proinflammatory cytokines is regulated by their receptor expression, downregulation and shedding, by specific inhibitors, and by inhibitory cytokines mainly produced by lymphocytes. This review aims to pinpoint recent findings in the assessment of the biologic activities of cytokine inhibitors and inhibitory cytokines. The suitability of these agents as therapeutic tools is discussed.
Language
  • English
Open access status
closed
Identifiers
Persistent URL
https://sonar.ch/global/documents/145343
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