Journal article
Health Economic Evaluation of an Influenza Vaccination Program to Prevent Sick Leave in Employees: A Prospective Cohort Study.
- Lutz N Vrije Universiteit Brussel, Department of Movement and Sport Sciences, Brussel, Belgium (Mr Lutz, Dr Deliens, Dr Clarys, Dr Taeymans); Bern University of Applied Sciences - Health, Bern Switzerland (Mr Lutz, Dr Taeymans); Ghent University - Faculty of medicine, Department of Public Health and Primary Care, Interuniversity Centre for Health Economics Research (I-CHER), Ghent, Belgium (Dr Verhaeghe).
- Deliens T
- Clarys P
- Verhaeghe N
- Taeymans J
- 2020-05-03
Published in:
- Journal of occupational and environmental medicine. - 2020
English
OBJECTIVE
To evaluate the cost-effectiveness of an influenza vaccination program (IVP) among employees.
METHODS
This health economic evaluation was embedded in a prospective cohort study of a voluntary IVP. Data on incidence, direct, and indirect costs were collected via questionnaires. Bootstrapping and modeling techniques were used to assess uncertainty of the results.
RESULTS
In the base-scenario, the IVP was less effective, more expensive and thus, neither cost-effective nor cost-beneficial. When applying a sensitivity analysis using published estimates of IVP effectiveness on the data, the IVP became cost-effective and cost-beneficial.
CONCLUSIONS
Like in many evaluations of real-world settings, lack of randomization may have caused selection bias which may explain the surprising results of the main analysis. This indicates the importance of sensitivity analyses and modeling approaches for future studies assessing the cost-effectiveness of IVP in a real-world setting.
To evaluate the cost-effectiveness of an influenza vaccination program (IVP) among employees.
METHODS
This health economic evaluation was embedded in a prospective cohort study of a voluntary IVP. Data on incidence, direct, and indirect costs were collected via questionnaires. Bootstrapping and modeling techniques were used to assess uncertainty of the results.
RESULTS
In the base-scenario, the IVP was less effective, more expensive and thus, neither cost-effective nor cost-beneficial. When applying a sensitivity analysis using published estimates of IVP effectiveness on the data, the IVP became cost-effective and cost-beneficial.
CONCLUSIONS
Like in many evaluations of real-world settings, lack of randomization may have caused selection bias which may explain the surprising results of the main analysis. This indicates the importance of sensitivity analyses and modeling approaches for future studies assessing the cost-effectiveness of IVP in a real-world setting.
- Language
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- English
- Open access status
- closed
- Identifiers
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- DOI 10.1097/JOM.0000000000001878
- PMID 32358470
- Persistent URL
- https://sonar.ch/global/documents/145902
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