Nanoconfined water can orient and cause long-range dipolar interactions with biomolecules.
- Hegemann D Empa, Swiss Federal Laboratories for Materials Science and Technology, Laboratory for Advanced Fibers, Lerchenfeldstrasse 5, 9014, St.Gallen, Switzerland. dirk.hegemann@empa.ch.
- Hocquard N Empa, Swiss Federal Laboratories for Materials Science and Technology, Laboratory for Advanced Fibers, Lerchenfeldstrasse 5, 9014, St.Gallen, Switzerland.
- Heuberger M Empa, Swiss Federal Laboratories for Materials Science and Technology, Laboratory for Advanced Fibers, Lerchenfeldstrasse 5, 9014, St.Gallen, Switzerland. manfred.heuberger@empa.ch.
- 2017-12-21
Published in:
- Scientific reports. - 2017
English
Surface properties are generally determined by the top most surface layer also defining how molecules adsorb onto it. By exploring effects due to interactions with deeper subsurface layers, however, long-range interaction forces were found to also significantly contribute to molecular adsorption, in which hydration of the subsurface region is the key factor. Water molecules confined to a subsurface amphiphilic gradient are confirmed to cause these long-range dipolar interactions by preferential orientation, thus significantly changing the way how a protein interacts with the surface. These findings imply future exploitation of an additional factor to modulate adsorption processes.
- Language
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- English
- Open access status
- gold
- Identifiers
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- DOI 10.1038/s41598-017-18258-1
- PMID 29259309
- Persistent URL
- https://sonar.ch/global/documents/145940
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