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Structure and biology of self lipid antigens.
Journal article

Structure and biology of self lipid antigens.

  • De Libero G Department of Research, University Hospital, Basel, Switzerland. gennaro.delibero@unibas.ch
  • Mori L
  • 2007-06-28
Published in:
  • Current topics in microbiology and immunology. - 2007
Animals
Antigens, CD1
Glycolipids
Guillain-Barre Syndrome
Humans
Lipid Metabolism
Lymphocyte Activation
Mice
Multiple Sclerosis
T-Lymphocytes
English Self lipid antigens induce selection and expansion of autoreactive T cells which have a role in immunoregulation and disease pathogenesis. Here we review the important biological rules which determine lipid immunogenicity. The impact of lipid structure, synthesis, traffic, membrane distribution and CD1 loading are discussed.
Language
  • English
Open access status
closed
Identifiers
Persistent URL
https://sonar.ch/global/documents/15155
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