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Methods for Measuring ctDNA in Lymphomas.
Journal article

Methods for Measuring ctDNA in Lymphomas.

  • Rossi D Division of Hematology, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland. davide.rossi@eoc.ch.
  • Condoluci A Division of Hematology, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland.
  • Spina V Laboratory of Experimental Hematology, Institute of Oncology Research, Bellinzona, Switzerland.
  • Gaidano G Division of Hematology, Department of Translational Medicine, University of Eastern Piedmont, Novara, Italy.
  • 2018-10-24
Published in:
  • Methods in molecular biology (Clifton, N.J.). - 2019
Genotyping
Liquid biopsy
Lymphomas
Next-generation sequencing
cfDNA
Biomarkers, Tumor
Cell-Free Nucleic Acids
Circulating Tumor DNA
DNA, Neoplasm
High-Throughput Nucleotide Sequencing
Humans
Lymphoma
Mutation
English Plasma cell-free DNA (cfDNA) is an easily accessible source of tumor DNA that allows accurate profiling of lymphoma patients, representing a complementary source of tumor DNA to tissue biopsy for genotyping. Applications of cfDNA analysis in lymphomas include: (1) identification of tumor mutations in a biopsy-free manner; (2) tracking tumor clonal evolution and identification of mutations causing resistance to treatment; and (3) monitoring of residual disease after therapy.
Language
  • English
Open access status
closed
Identifiers
Persistent URL
https://sonar.ch/global/documents/154527
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