Journal article
Quality of life after pulmonary embolism: Prospective validation of the German version of the PEmb-QoL questionnaire.
- Frey PM Department of General Internal Medicine, Bern University Hospital, Bern, Switzerland. Electronic address: pascal.frey@insel.ch.
- Méan M Department of General Internal Medicine, Bern University Hospital, Bern, Switzerland; Department of General Internal Medicine, Lausanne University Hospital, Lausanne, Switzerland.
- Limacher A CTU Bern, Department of Clinical Research, and Institute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland.
- Leiss W Department of General Internal Medicine, Bern University Hospital, Bern, Switzerland.
- Schwab N Department of General Internal Medicine, Bern University Hospital, Bern, Switzerland.
- Rochat M Department of General Internal Medicine, Lausanne University Hospital, Lausanne, Switzerland.
- Aujesky D Department of General Internal Medicine, Bern University Hospital, Bern, Switzerland.
- 2015-04-19
Published in:
- Thrombosis research. - 2015
Pulmonary Embolism
Quality of Life
Questionnaires
Validation Studies
Activities of Daily Living
Adult
Aged
Aged, 80 and over
Female
Humans
Language
Male
Middle Aged
Patient Discharge
Prospective Studies
Psychometrics
Pulmonary Embolism
Quality of Life
Reproducibility of Results
Surveys and Questionnaires
Switzerland
Young Adult
English
BACKGROUND
The Pulmonary Embolism Quality of Life questionnaire (PEmb-QoL) is a 40-item questionnaire to measure health-related quality of life in patients with pulmonary embolism. It covers six 6 dimensions: frequency of complaints, limitations in activities of daily living, work-related problems, social limitations, intensity of complaints, and emotional complaints. Originally developed in Dutch and English, we prospectively validated a German version of the PEmb-QoL.
METHODS
A forward-backward translation of the English version of the PEmb-QoL into German was performed. German-speaking consecutive adult patients aged ≥18 years with an acute, objectively confirmed pulmonary embolism discharged from a Swiss university hospital (01/2011-06/2013) were recruited telephonically. Established psychometric tests and criteria were used to evaluate the acceptability, reliability, and validity of the German PEmb-QoL questionnaire. To assess the underlying dimensions, an exploratory factor analysis was performed.
RESULTS
Overall, 102 patients were enrolled in the study. The German version of the PEmb-QoL showed a good internal consistency (Cronbach's alpha ranging from 0.72 to 0.96), item-total (0.53-0.95) and inter-item correlations (>0.4), and test-retest reliability (intra-class correlation coefficients 0.59-0.89) for the dimension scores. A moderate correlation of the PEmb-QoL with SF-36 dimension and summary scores (0.21-0.83) indicated convergent validity, while low correlations of PEmb-QoL dimensions with clinical characteristics (-0.16-0.37) supported discriminant validity. The exploratory factor analysis suggested four underlying dimensions: limitations in daily activities, symptoms, work-related problems, and emotional complaints.
CONCLUSION
The German version of the PEmb-QoL questionnaire is a valid and reliable disease-specific measure for quality of life in patients with pulmonary embolism.
The Pulmonary Embolism Quality of Life questionnaire (PEmb-QoL) is a 40-item questionnaire to measure health-related quality of life in patients with pulmonary embolism. It covers six 6 dimensions: frequency of complaints, limitations in activities of daily living, work-related problems, social limitations, intensity of complaints, and emotional complaints. Originally developed in Dutch and English, we prospectively validated a German version of the PEmb-QoL.
METHODS
A forward-backward translation of the English version of the PEmb-QoL into German was performed. German-speaking consecutive adult patients aged ≥18 years with an acute, objectively confirmed pulmonary embolism discharged from a Swiss university hospital (01/2011-06/2013) were recruited telephonically. Established psychometric tests and criteria were used to evaluate the acceptability, reliability, and validity of the German PEmb-QoL questionnaire. To assess the underlying dimensions, an exploratory factor analysis was performed.
RESULTS
Overall, 102 patients were enrolled in the study. The German version of the PEmb-QoL showed a good internal consistency (Cronbach's alpha ranging from 0.72 to 0.96), item-total (0.53-0.95) and inter-item correlations (>0.4), and test-retest reliability (intra-class correlation coefficients 0.59-0.89) for the dimension scores. A moderate correlation of the PEmb-QoL with SF-36 dimension and summary scores (0.21-0.83) indicated convergent validity, while low correlations of PEmb-QoL dimensions with clinical characteristics (-0.16-0.37) supported discriminant validity. The exploratory factor analysis suggested four underlying dimensions: limitations in daily activities, symptoms, work-related problems, and emotional complaints.
CONCLUSION
The German version of the PEmb-QoL questionnaire is a valid and reliable disease-specific measure for quality of life in patients with pulmonary embolism.
- Language
-
- English
- Open access status
- closed
- Identifiers
-
- DOI 10.1016/j.thromres.2015.03.031
- PMID 25887632
- Persistent URL
- https://sonar.ch/global/documents/155208
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