Dual-channel electrospray microchip.
- Lu Y Laboratoire d'Electrochimie Physique et Analytique, Station 6, Ecole Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland.
- Liu F
- Lion N
- Girault HH
- 2013-02-07
Published in:
- Journal of the American Society for Mass Spectrometry. - 2013
Buffers
Equipment Design
Microarray Analysis
Peptides
Solutions
Spectrometry, Mass, Electrospray Ionization
Water
English
A dual-channel electrospray microchip has been developed for electrospray ionization mass spectrometry (ESI-MS) where aqueous samples are mixed at the Taylor cone with an organic buffer. Due to the fast and effective mixing in the Taylor cone, the aqueous sample can be well ionized with a high ion intensity. The influence of geometric parameters such as the distance between the two microchannels at their junction at the tip of the emitter has been investigated together with chemical parameters such as the organic buffer composition.
- Language
-
- English
- Open access status
- green
- Identifiers
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- DOI 10.1007/s13361-012-0547-z
- PMID 23385957
- Persistent URL
- https://sonar.ch/global/documents/155840
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