A role for angiopoietin-2 in organ-specific metastasis.

Rigamonti N; De Palma M

doi:10.1016/j.celrep.2013.07.034

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Journal article

A role for angiopoietin-2 in organ-specific metastasis.

Rigamonti N The Swiss Institute for Experimental Cancer Research ISREC, School of Life Sciences, Swiss Federal Institute of Technology Lausanne EPFL, 1015 Lausanne, Switzerland.
De Palma M

2013-09-03

Published in:

Cell reports. - 2013

English Angiopoietin-2 (ANG2/ANGPT2) has recently emerged as a promising target for the inhibition of tumor metastasis. In this issue of Cell Reports, Minami et al. show that the calcineurin-NFAT pathway promotes pulmonary tumor metastasis by inducing ANG2 in the lung endothelium.

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