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Establishing Causality: Opportunities of Synthetic Communities for Plant Microbiome Research.

  • Vorholt JA Institute of Microbiology, ETH Zurich, 8093 Zurich, Switzerland. Electronic address: jvorholt@ethz.ch.
  • Vogel C Institute of Microbiology, ETH Zurich, 8093 Zurich, Switzerland.
  • Carlström CI Institute of Microbiology, ETH Zurich, 8093 Zurich, Switzerland.
  • Müller DB Institute of Microbiology, ETH Zurich, 8093 Zurich, Switzerland.
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  • 2017-08-12
Published in:
  • Cell host & microbe. - 2017
gnotobiotic
holobiont
leaf
metaorganism
microbiome
microbiota
phyllosphere
rhizosphere
root
synthetic community
Bacteria
Bacterial Physiological Phenomena
Ecosystem
Host-Pathogen Interactions
Metagenome
Microbial Consortia
Microbial Interactions
Microbiota
Plant Roots
Plants
Soil Microbiology
English Plant microbiome research highlights the importance of indigenous microbial communities for host phenotypes such as growth and health. It aims to discover the molecular basis by which host-microbe and microbe-microbe interactions shape and maintain microbial communities and to understand the role of individual microorganisms, as well as their collective ecosystem function. Here, we discuss reductionist approaches to disentangle the inherent complexity of interactions in situ. Experimentally tractable, synthetic communities enable testing of hypotheses by targeted manipulation in gnotobiotic systems. Modifications of microbial, host, and environmental parameters allow for the quantitative assessment of host and microbe characteristics with dynamic and spatial resolution. We summarize first insights from this emerging field and discuss current challenges and limitations. Using multifaceted approaches to detect interactions and functions will provide new insights into the fundamental biology of plant-microbe interactions and help to harness the power of the microbiome.
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  • English
Open access status
bronze
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Persistent URL
https://sonar.ch/global/documents/158714
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