Biomarkers in renal cancer.
- Moch H Institute of Surgical Pathology, University Hospital Zurich, Schmelzbergstrasse 12, CH-8091, Zürich, Switzerland, holger.moch@usz.ch.
- Srigley J
- Delahunt B
- Montironi R
- Egevad L
- Tan PH
- 2014-02-04
Published in:
- Virchows Archiv : an international journal of pathology. - 2014
Biomarkers, Tumor
Consensus Development Conferences as Topic
Humans
Kidney Neoplasms
Mutation
Neoplasm Staging
Prognosis
English
Treatment options for primary and metastatic renal cancer are increasing. Accurate data from the pathological examination of renal cancer specimens aid clinicians in stratifying patients for surveillance and adjuvant therapies. This review focuses on biomarkers in diagnosis, prognosis and prediction of the biologic behavior of renal tumors which should be recorded in pathology reports and which are under investigation. Special emphasis is given to the use of immunohistochemical markers in differential diagnosis of various renal tumor subtypes. The relevance of cytogenetic and molecular findings is also discussed. The review includes the 2012 International Society for Urological Pathology Consensus conference recommendations.
- Language
-
- English
- Open access status
- green
- Identifiers
-
- DOI 10.1007/s00428-014-1546-1
- PMID 24487793
- Persistent URL
- https://sonar.ch/global/documents/160994
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