Hope for CKD-MBD Patients: New Diagnostic Approaches for Better Treatment of CKD-MBD.
- 2017-08-09
Published in:
- Kidney diseases (Basel, Switzerland). - 2017
Biomarker
Calcification propensity
Chronic kidney disease-mineral and bone disorder
Morbidity
Mortality
Nonoxidized parathyroid hormone
T50 test
English
BACKGROUND
Chronic kidney disease-mineral and bone disorder (CKD-MBD) patients have a huge morbidity and mortality. Only relatively minor progress in therapeutic strategies has been made in the past decades. This is at least partially due to a lack of predictive diagnostic tools allowing personalized treatment of CKD-MBD patients.
SUMMARY
In this review we describe recent progress in the diagnosis of disturbances of calcium and phosphate metabolism in patients with CKD-MBD, measuring biological active nonoxidized parathyroid hormone as well as the overall likelihood of a patient to get calcified.
KEY MESSAGE
There is hope. The new tools have the potential of allowing personalized therapy for the treatment of CKD-MBD and hence improving outcome.
Chronic kidney disease-mineral and bone disorder (CKD-MBD) patients have a huge morbidity and mortality. Only relatively minor progress in therapeutic strategies has been made in the past decades. This is at least partially due to a lack of predictive diagnostic tools allowing personalized treatment of CKD-MBD patients.
SUMMARY
In this review we describe recent progress in the diagnosis of disturbances of calcium and phosphate metabolism in patients with CKD-MBD, measuring biological active nonoxidized parathyroid hormone as well as the overall likelihood of a patient to get calcified.
KEY MESSAGE
There is hope. The new tools have the potential of allowing personalized therapy for the treatment of CKD-MBD and hence improving outcome.
- Language
-
- English
- Open access status
- gold
- Identifiers
-
- DOI 10.1159/000477244
- PMID 28785559
- Persistent URL
- https://sonar.ch/global/documents/165658
Statistics
Document views: 28
File downloads:
- Full-text: 0