Hope for CKD-MBD Patients: New Diagnostic Approaches for Better Treatment of CKD-MBD.

Hocher B; Pasch A

doi:10.1159/000477244

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Journal article

Hope for CKD-MBD Patients: New Diagnostic Approaches for Better Treatment of CKD-MBD.

Hocher B Institute of Nutritional Science, University of Potsdam, Potsdam-Rehbrücke, Germany.
Pasch A Department of Clinical Research, University Hospital Bern, University of Bern, Bern, Switzerland.

2017-08-09

Published in:

Kidney diseases (Basel, Switzerland). - 2017

Chronic kidney disease-mineral and bone disorder

Nonoxidized parathyroid hormone

English BACKGROUND
Chronic kidney disease-mineral and bone disorder (CKD-MBD) patients have a huge morbidity and mortality. Only relatively minor progress in therapeutic strategies has been made in the past decades. This is at least partially due to a lack of predictive diagnostic tools allowing personalized treatment of CKD-MBD patients.

SUMMARY
In this review we describe recent progress in the diagnosis of disturbances of calcium and phosphate metabolism in patients with CKD-MBD, measuring biological active nonoxidized parathyroid hormone as well as the overall likelihood of a patient to get calcified.

KEY MESSAGE
There is hope. The new tools have the potential of allowing personalized therapy for the treatment of CKD-MBD and hence improving outcome.

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