Guidelines on eosinophilic esophagitis: evidence-based statements and recommendations for diagnosis and management in children and adults.
- Lucendo AJ Department of Gastroenterology, Hospital General de Tomelloso, Servicio de Salud de Castilla-La Mancha, Tomelloso, Spain.
- Molina-Infante J Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Madrid, Spain.
- Arias Á Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Madrid, Spain.
- von Arnim U Department of Gastroenterology, Hepatology and Infectious Diseases, Otto von Guericke University, Magdeburg, Germany.
- Bredenoord AJ Department of Gastroenterology and Hepatology, Academic Medical Centre, Amsterdam, the Netherlands.
- Bussmann C Pathologie Viollier, Basel, Switzerland.
- Amil Dias J Department of Pediatrics, Hospital S. João, Porto, Portugal.
- Bove M Department of ENT, Head and Neck Surgery, NÄL Medical Centre, Trollhättan, Sweden.
- González-Cervera J Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Madrid, Spain.
- Larsson H Department of ENT, Head and Neck Surgery, NÄL Medical Centre, Trollhättan, Sweden.
- Miehlke S Center for Digestive Diseases, Internal Medicine Center Eppendorf, Hamburg, Germany.
- Papadopoulou A Division of Pediatric Gastroenterology and Hepatology, Athens Children's Hospital "Agia Sofia", University of Athens, Athens, Greece.
- Rodríguez-Sánchez J Department of Gastroenterology, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain.
- Ravelli A University Department of Pediatrics, Children's Hospital - Spedali Civili, Brescia, Italy.
- Ronkainen J Center for Life Course Health Research, University of Oulu, Tornio, Finland.
- Santander C Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Madrid, Spain.
- Schoepfer AM Division of Gastroenterology and Hepatology, Centre Hospitalier Universitaire Vaudois et Université de Lausanne, Lausanne, Switzerland.
- Storr MA Center of Endoscopy, Starnberg, Germany.
- Terreehorst I Department of ENT, Amsterdam Medical Centre, Amsterdam, the Netherlands.
- Straumann A Swiss EoE Clinics, Olten, Switzerland.
- Attwood SE Department of Health Services Research, Durham University, UK.
- 2017-05-17
Published in:
- United European gastroenterology journal. - 2017
English
INTRODUCTION
Eosinophilic esophagitis (EoE) is one of the most prevalent esophageal diseases and the leading cause of dysphagia and food impaction in children and young adults. This underlines the importance of optimizing diagnosys and treatment of the condition, especially after the increasing amount of knowledge on EoE recently published. Therefore, the UEG, EAACI ESPGHAN, and EUREOS deemed it necessary to update the current guidelines regarding conceptual and epidemiological aspects, diagnosis, and treatment of EoE.
METHODS
General methodology according to the Appraisal of Guidelines for Research and Evaluation (AGREE) II and the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system was used in order to comply with current standards of evidence assessment in formulation of recommendations. An extensive literature search was conducted up to August 2015 and periodically updated. The working group consisted of gastroenterologists, allergists, pediatricians, otolaryngologists, pathologists, and epidemiologists. Systematic evidence-based reviews were performed based upon relevant clinical questions with respect to patient-important outcomes.
RESULTS
The guidelines include updated concept of EoE, evaluated information on disease epidemiology, risk factors, associated conditions, and natural history of EoE in children and adults. Diagnostic conditions and criteria, the yield of diagnostic and disease monitoring procedures, and evidence-based statements and recommendation on the utility of the several treatment options for patients EoE are provided. Recommendations on how to choose and implement treatment and long-term management are provided based on expert opinion and best clinical practice.
CONCLUSION
Evidence-based recommendations for EoE diagnosis, treatment modalities, and patients' follow up are proposed in the guideline.
Eosinophilic esophagitis (EoE) is one of the most prevalent esophageal diseases and the leading cause of dysphagia and food impaction in children and young adults. This underlines the importance of optimizing diagnosys and treatment of the condition, especially after the increasing amount of knowledge on EoE recently published. Therefore, the UEG, EAACI ESPGHAN, and EUREOS deemed it necessary to update the current guidelines regarding conceptual and epidemiological aspects, diagnosis, and treatment of EoE.
METHODS
General methodology according to the Appraisal of Guidelines for Research and Evaluation (AGREE) II and the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system was used in order to comply with current standards of evidence assessment in formulation of recommendations. An extensive literature search was conducted up to August 2015 and periodically updated. The working group consisted of gastroenterologists, allergists, pediatricians, otolaryngologists, pathologists, and epidemiologists. Systematic evidence-based reviews were performed based upon relevant clinical questions with respect to patient-important outcomes.
RESULTS
The guidelines include updated concept of EoE, evaluated information on disease epidemiology, risk factors, associated conditions, and natural history of EoE in children and adults. Diagnostic conditions and criteria, the yield of diagnostic and disease monitoring procedures, and evidence-based statements and recommendation on the utility of the several treatment options for patients EoE are provided. Recommendations on how to choose and implement treatment and long-term management are provided based on expert opinion and best clinical practice.
CONCLUSION
Evidence-based recommendations for EoE diagnosis, treatment modalities, and patients' follow up are proposed in the guideline.
- Language
-
- English
- Open access status
- bronze
- Identifiers
-
- DOI 10.1177/2050640616689525
- PMID 28507746
- Persistent URL
- https://sonar.ch/global/documents/1687
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